Protein Info for mRNA_1648 in Rhodosporidium toruloides IFO0880

Name: 10016
Annotation: K11436 PRMT3 type I protein arginine methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 PF05185: PRMT5" amino acids 223 to 335 (113 residues), 23 bits, see alignment E=3e-08 PF13489: Methyltransf_23" amino acids 256 to 307 (52 residues), 27.1 bits, see alignment 1.5e-09 PF02475: Met_10" amino acids 259 to 336 (78 residues), 25.9 bits, see alignment E=3.5e-09 PF13847: Methyltransf_31" amino acids 259 to 369 (111 residues), 37.7 bits, see alignment E=8.2e-13 PF06325: PrmA" amino acids 259 to 339 (81 residues), 49 bits, see alignment E=2.6e-16 PF05175: MTS" amino acids 259 to 331 (73 residues), 33.1 bits, see alignment E=1.9e-11 PF13649: Methyltransf_25" amino acids 263 to 337 (75 residues), 41.6 bits, see alignment E=7.9e-14 PF08241: Methyltransf_11" amino acids 264 to 334 (71 residues), 32.6 bits, see alignment E=4.7e-11

Best Hits

Predicted SEED Role

"Protein arginine N-methyltransferase 1 (EC 2.1.1.-)" in subsystem Dimethylarginine metabolism (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (568 amino acids)

>mRNA_1648 K11436 PRMT3 type I protein arginine methyltransferase (Rhodosporidium toruloides IFO0880)
MASQTHSDSGSDSDNTWDDWDDGNQPARSLFEPAAEFPTAWLALDHDRRTHGVDLPLLAS
TLDFFERIRLINWIRATNPDPASLRRLDRNAAFLDDDQYLKPVLEDDALLQVDFDTLSLD
GPPSGARPSSSSAAPSSSNPPMPSIDDPLTPSDLIETLKAHLADAQAANEHLRRIVKERL
GGEMGLGEGDRLGEVVEGVEKVSVKGKEKEGGEAVHKDDDHYYESYQYNDIHEIMLKDRV
RTLAYRSFILHPSNAARFKGKVVLDVGCGTGILSMFAAQAGAKKVYAVDASNVAFKAMRN
VKANGFEGVIEVIKGKVEEINLPSKVDVIISEWMGYCLLYECMLDSVLYARDKYLSPSGL
MVPSQTSILWSAYAGQGWYDDRVKFWDEVYGFEMKAMKEKIEDEAIIEVMDEGEVVSSEV
SIADIFTQTATIASLSFTSPLSLAITRAPANTDSSAPFTMYGFLAHFDTYFTSAPRLADS
SKRAASVSESDGEVFFTTGAWSTPTHWKQTFFLLREPIQVRVGDKVEGEVKVGKNEDNSR
ELSVEVVWSVVGSEGEKRSEGVQAWKVR