Protein Info for mRNA_1829 in Rhodosporidium toruloides IFO0880

Name: 10197
Annotation: K20238 E2.1.1.317 sphingolipid C9-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 transmembrane" amino acids 31 to 49 (19 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details PF02353: CMAS" amino acids 175 to 450 (276 residues), 227.5 bits, see alignment E=6e-71 PF08123: DOT1" amino acids 218 to 300 (83 residues), 29.3 bits, see alignment E=1.8e-10 PF13489: Methyltransf_23" amino acids 219 to 348 (130 residues), 36.3 bits, see alignment E=1.5e-12 PF13649: Methyltransf_25" amino acids 241 to 337 (97 residues), 41.9 bits, see alignment E=4.3e-14 PF08242: Methyltransf_12" amino acids 241 to 339 (99 residues), 34.9 bits, see alignment E=6.4e-12 PF08241: Methyltransf_11" amino acids 241 to 341 (101 residues), 40.6 bits, see alignment E=1e-13

Best Hits

Swiss-Prot: 54% identical to C9MT_KOMPG: Sphingolipid C9-methyltransferase (PAS_chr4_0465) from Komagataella phaffii (strain GS115 / ATCC 20864)

KEGG orthology group: None (inferred from 67% identity to lbc:LACBIDRAFT_295662)

MetaCyc: 54% identical to sphingolipid C9-methyltransferase (Komagataella pastoris)
RXN-16336 [EC: 2.1.1.317]

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.317 or 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>mRNA_1829 K20238 E2.1.1.317 sphingolipid C9-methyltransferase (Rhodosporidium toruloides IFO0880)
MAATYDPTVGLKVTHRAAIANAPFPVEGNGSFSNVQLAAAVLIVPYFLSRFVPYFSFRTT
YVFLLILTGIPTTIAYWLLMSRANVRVRDSGIFPGKDIEHYITIKDAELREKYNGQKKIP
MQVFHDAYFEGKIDIKGNMLELLEWRHDWMSFPMTLELMKYVLTKLIPDVIFHSAGQDEE
QVTDHYDRGDDFHEWFLGPRMIYTSGIIHDVDRKETLEELQDNKLAVVCQKLQLKPTDTL
LDIGCGWGTLVTYAAKNYGCDATGVTLSKNQAEFGTKRIADNGVDASKARILRTDFRNLD
KSKKFSKIVSLEMAEHVGIRRYNTFLRDVYNLLDDDGILVFQVAGIRPSWQYEDLIWGLF
MNKYVFPGADASCALNWVIGRLENAGFEVTNVDVLGVHYSATLHRWYENWIKNKENVLAK
YGERWYRVWLYFLASSVITSRQGGASVFQITLHKNLNSYHRVDDIPSHTNIFPKLEREPQ
LVV