Protein Info for mRNA_1837 in Rhodosporidium toruloides IFO0880

Name: 10205
Annotation: K00281 GLDC, gcvP glycine dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1061 transmembrane" amino acids 849 to 868 (20 residues), see Phobius details PF02347: GDC-P" amino acids 66 to 505 (440 residues), 570.9 bits, see alignment E=9e-176

Best Hits

Predicted SEED Role

"Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2)" in subsystem Glycine and Serine Utilization or Glycine cleavage system or Photorespiration (oxidative C2 cycle) (EC 1.4.4.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1061 amino acids)

>mRNA_1837 K00281 GLDC, gcvP glycine dehydrogenase (Rhodosporidium toruloides IFO0880)
MLRRISSTVPRRPISAISPAAPTRFAARARTPRSQLALRSFATGLSQDATPTPTSSVFAP
LDTFTRRHVGPQEHSIRKMLDYLGYESLDAFVADCVPEDIRLPEDAVSAEGKDGIRALSE
TELLRRAKELGRKNKVTRSFIGLGYHQAVLPQVILRNILENHGWFSQYSPYQAEISQGRL
ESLINFQSLTTSLTGLDIANASLLDEGTAAAEGMIMAFGQAREKRKTIFVDRSVLPQTVG
VAKTRAEPFGIKVVVGDVRSLLSEESGDKEQHKDLLGVLVQYPEMRGEVTDWEAMAKRTH
DLGGLVLCATDFLALTMLKPPGEWGADIAFGNAARFGVPLGYGGPHAAFFACTGKLKRRM
PGRLIGLSKDAEGRPAYRLALQTREQHIRREKATSNICTAQALLANISAMYAVYHGPEGL
RQIAEKVHGLARVVAAAVEKLGHKVLNPTYFDSLTIRLGGTAASVLHEAAVAKDINLRRV
DDHHVAVTFDESHSLEDVLDLLNVFVSIQTSVKSRQLQPFTDESLIAFAQSIGVQAPKPM
RATLGQKSSGEGIPPIESPAIPSNLARTSPFLTQSVWNSHHSETDLIRYMHHLQSKDLSL
VHAPIPLGSCTMKLNPTTAMTPFTWDEFAKIHPFAPADQARGYKEMTDELAHDLSKLTGL
PGCSLQPNSGAQGEYAGLSVIRAYHRSRGDEHRNICLIPASAHGTNPASAIMAGMRVVPV
KNLADGSLDLADLEAKVEQHRDNLAAFMVTYPSTFGVFEDTITKACRLINENGGQVYFDG
ANFNSMMGLTSPGQVGAGAVHLNLHKTMAIPHGGGGPGMGPICVAEHLIPFLPGNPVVPS
ASKDAIGPISAAPFGSASILSISWAFIKMLGADGLKLSSKLALLNANYAMNRLKDHYRVK
FVNKNGRCAHEFLIDLAEFDDKAGLKVMDIAKRLQDFGIHPPTCSWPISTAMLIEPTESE
GLRDIDLFCDAMIKIRQEIDEIIEGKQPRDNNIITNAPHTQQVLLAEKWDRPYSREEAAY
PMKSLRTRKFWPTVSRVDDKYGDLNLFCECSDVEAYADVDA