Protein Info for mRNA_1844 in Rhodosporidium toruloides IFO0880

Name: 10212
Annotation: K16066 ydfG 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 19 to 41 (23 residues), see Phobius details PF00106: adh_short" amino acids 13 to 209 (197 residues), 179.2 bits, see alignment E=9.9e-57 PF08659: KR" amino acids 14 to 181 (168 residues), 57.1 bits, see alignment E=3.6e-19 PF13561: adh_short_C2" amino acids 19 to 240 (222 residues), 123.5 bits, see alignment E=1.5e-39

Best Hits

Swiss-Prot: 45% identical to YI13_SCHPO: NADP-dependent 3-hydroxy acid dehydrogenase (SPAC521.03) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 65% identity to uma:UM03591.1)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>mRNA_1844 K16066 ydfG 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase (Rhodosporidium toruloides IFO0880)
MAGVFSAQRLAGKTVLVTGASGGIGAATAILFARAGASLILTARRQAQLDEVKRAAEQAN
KEGATGKGGKVVTLTLDMQDRKQIKGLLDRIPEELREVDVLVNNAGLVYGREQVGDIDED
EIDTMINTNVVGLISLTQIFVKEFKKRNRGHVINLGSIAGIEPYAGGSIYCATKHAVHAF
NGSLLRELVGWNIRVTCIAPGMVETNFSITRFRGDEDAAKKVYEGITPLSANDIAEEIVW
AASRPEHVNIADVLVFPSAQASAIINHRGPQNGGK