Protein Info for mRNA_1850 in Rhodosporidium toruloides IFO0880

Name: 10218
Annotation: K00311 ETFDH electron-transferring-flavoprotein dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 PF13450: NAD_binding_8" amino acids 96 to 141 (46 residues), 26.7 bits, see alignment 1.4e-09 PF05187: ETF_QO" amino acids 535 to 644 (110 residues), 140.1 bits, see alignment E=6.7e-45

Best Hits

Swiss-Prot: 52% identical to ETFD_DICDI: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (etfdh) from Dictyostelium discoideum

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 73% identity to cne:CNA04420)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (646 amino acids)

>mRNA_1850 K00311 ETFDH electron-transferring-flavoprotein dehydrogenase (Rhodosporidium toruloides IFO0880)
MLRSTGHAARSLGSPAPALTRRAAASLPARLPTSSIPLATRSGPSALANRNASRLALPAS
LRTFTSTPRARQAEPVDQELDFEGVERVQDEVDVCIVGGGPAGLSAAIQLMKMAQEKGEE
IRVVVLEKGAEVGAHILSGAVIEPRALDELIPDWKEKGAPLNQEALSDSMRWLTPTGSFA
MPHPPQMSNKGNYIISLSKLTRWLGEQAEELGVEIYPGFAGAKILYTEDGTGVRGVQTND
IGLDKNFKPKDSFEPGMEFLAKVTILAEGCHGSLSKQIQGKFNLREGKDPQTYGLGVKEV
WKVKPEKHEPGKVQHTLGWPLDNSTYGGTWLYHMEDEMVSLGIVVGLDYKNPYISPYKEL
QRLKHHPLFADLLEGGECIAYGARALNEGGYQSIPKLTFPGGAMIGDSAGFLNVPKIKGT
HTSMKSGMLAAEAAFNAITSSRASESDSSETALDVSEYEKLFEESWVAKELKEVRNLRPS
FHTSLGNFGGIIYSGIDSLLLKGRVPWTFHHPEEDYAATLPARQFKEIDYPKPDGKLSFD
ILESVSRTNTYHAEDQPVHLHIEPSARAAHVKTNVKQYAGLLGRVCPAAVYEYVDAEGTE
EDAEGKRLVINSQNCIHCKTCSIKVPTQDIQWRVPEGSGGPRYECT