Protein Info for mRNA_1878 in Rhodosporidium toruloides IFO0880

Name: 10246
Annotation: K01875 SARS, serS seryl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 PF02403: Seryl_tRNA_N" amino acids 3 to 122 (120 residues), 61.3 bits, see alignment E=9.7e-21 TIGR00414: serine--tRNA ligase" amino acids 10 to 452 (443 residues), 463.5 bits, see alignment E=3.4e-143 PF00587: tRNA-synt_2b" amino acids 247 to 436 (190 residues), 129.6 bits, see alignment E=1.3e-41

Best Hits

KEGG orthology group: K01875, seryl-tRNA synthetase [EC: 6.1.1.11] (inferred from 61% identity to scm:SCHCODRAFT_77152)

Predicted SEED Role

"Seryl-tRNA synthetase (EC 6.1.1.11)" in subsystem Glycine and Serine Utilization (EC 6.1.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>mRNA_1878 K01875 SARS, serS seryl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MGIDLQLLQNDKGGDFEGVCASQKKRFASEELVHEVLAMYKEWTKTQFDTQQLQKEVNKI
QKDIGACMKDMKDAAKKEEASKKVEELKAQKADMDAKIVGLRAQAVEQETAMRKKGNTIG
NIVHESVPVSDNEDNNKVERTFYPKDANGDSAPPVRGAGLTMKEGVLSHHEVMYRLGMLE
MERGTKVAGHRGYYLVGDGVDLNQALITYGLDFLRSKEYKKVQPPFFMNKAMMGKTAQLE
EFDEALYKLEGSNEDTEKYLIATSEQPISAMHADEWFEKPSEQLPIKYAGYSTCFRKEAG
SSGRDVLGVFRVHQFEKVEQFCITDPSSSWEMFDQMIANSEEFYQSLGLPYQLISIVSGA
LNNAAAKKYDLEAWFPHQGEYKELVSVSNCTDYQSRSLEVRCGIKKQGDTRKVYVHMLNG
TLCATERALCCIVENYQTPEGVMIPEPMQKYMQGRKFLPYVRELPTTAAQKPAKQKH