Protein Info for mRNA_1953 in Rhodosporidium toruloides IFO0880

Name: 10321
Annotation: K18442 ARFGEF, BIG brefeldin A-inhibited guanine nucleotide-exchange protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2092 transmembrane" amino acids 416 to 435 (20 residues), see Phobius details amino acids 677 to 694 (18 residues), see Phobius details PF16213: DCB" amino acids 251 to 339 (89 residues), 25.7 bits, see alignment (E = 1.7e-09) amino acids 416 to 479 (64 residues), 30 bits, see alignment (E = 8.3e-11) PF12783: Sec7_N" amino acids 641 to 810 (170 residues), 154.1 bits, see alignment E=5.9e-49 PF01369: Sec7" amino acids 985 to 1168 (184 residues), 243.7 bits, see alignment E=2.3e-76 PF09324: DUF1981" amino acids 1504 to 1586 (83 residues), 112.1 bits, see alignment (E = 1.9e-36)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2092 amino acids)

>mRNA_1953 K18442 ARFGEF, BIG brefeldin A-inhibited guanine nucleotide-exchange protein (Rhodosporidium toruloides IFO0880)
MAEEEHKPAIELEEPEAGPEVYREDEVEREHDEERVLSGDAEAATAGQGDAAVTDKAQDD
APEPLAEARTGSGEVEHDSLPLDDNSTHDESAQPPTTEDVPLSPPQSATSAPANEADEPG
DFEDVSLSRAPSVAPSAQVEALRQEIKRDAEELKNDTPVVQPTPAPVPDDAVEETQLGES
AATPAAEEVAESVHAEAPPAPSVPATTTASTATSSPHPESTATKPRRESLASVTTVSAPG
SSHLVSGILIVSSLESIAASKEAKKSKPLKDALDKALDALKTPVPATPGIGGGASTTIDP
HLVFLPLRLACETKSLQLQITALDCLGKLVSYDFFVEQHDPDAPQLRLGGGDDDNESLAG
GSTNQQQNFEALPLADQITATVCDCFSPSPNASSSSSSSSSSSSSASQATTPHDTLLLRL
LSCLLSLILSSSLPIHQSALLKAVRTVYNVFLLGRPGTVQTVAQATLGQIVGGVFGRIEL
PDALAKAAAKNASVEKGLGVSGIALSTPAASRSQSRTDLASVAEEEPPAPVEAEKTPKVP
PPAEEEKVEETPRVKQDGMNGATENGIADSGEKEADEKEPSAAGTADDARTPRVSVSQDE
SGSAADEVPQGEGQKITTENLARLNGTPIPPTDCVSTNDLYIKDAFLVFRALCKLSMKPL
GTDSERDLKSPAMRSKLLSLHLILTILNNHMSLFTDSQIAIISSTSRERTPFLTAVKQYL
CLALSRNAVSPVIQVFELSCEIFSRMLSGMRQRLKKEIEVLLNEIFLPILEMRNATVRQK
SLLLAAFARLAQDPQALVDIYLNYDCDRSSLDNIYERLLNIVSKLCTTHFPPTAPEGKAG
QPILSALSPAVSPFPLSATSLFDESRFANPSFAGTPPEAHLKRQSLECLVAVLRSLVSWA
GRGAVSGPAASVIGPSTSTTSLNGTHGRTSEDGNGATSPSPAPGAGPSDPRTSFFAGDRR
STSGTNTPDVVPADDPSRFENAKLRKTTLLEGIKKFNFKPKRGVAFLIESGFIRSSDPKD
VARFLLHADGLDKAQIGEYLGEGEPENIATMHAFVDFMDFNNMLFVDALRMFLQSFRLPG
EAQKIDRYMLKFAERYTAGNPGVFANADTAYILAFSVILLNTDAHNPQVKKPMSKVEFIK
NNRGIDDGKDIDEKYLSDIYDEINANEIRMKDEVEAAGPQAPAPGLAGAIATVGRDLQRE
AYLWQSESMVNKTEALFRTLVRGQRRGGRASDEYYSASHAEHVKPMFEVVWMAILAGISG
PLQDSDDLELISLSLDGFKQAIKIVCLFDLELERNAFVTTLAKFTFLNNFGEMRPKNVEA
IKTLLDVAMVDGNYLKGSWREVLTCVSQLERFQLIAQGVDSQTLPELGRKPSLSSKRRST
VTSKRIGRPTEEVAEGTRSQHLYITADMIFSSTPNLSGTAIVDFVQALSEVSWEEIQASG
LAEQPRVFCLQKLVEICYYNMNRIRLEWSAMWVIIGEHFNQVTCHTNAKVSFLALDSLRQ
LAMRFLEKEELANFKFQKDFLKPFENAMLHNTNPDARDMVLQCLHQMIQARVQNLRSGWR
TMFGVFAAAAKVSTERIAVQAFDIVQRVNKEHFAQIVEYGSFADLTVCVTDFCKISKFQR
VSLQAIELLKSLIPMMLACPACPLSQTANGAQVELTATDDPMLRFWFPLLFGFYDVIMNG
EDLEVRKRALDYLFDTLKKHGQSFPPEFWDTICKEVLFPIFAVLRSRSDVSRFSTHEDMS
VWLSTTMIQALRNLVDLFTYYFDVLARLLDKLLDLLSECICQGFADAARPAENDTLARIG
TSCLQQLVEDNVDKLSPPRWERIISTFLQLFKTTTAYQLFDPILLLPQADSPAAAQPASN
GFAPLSPSREEEQPVPPPKNGPVDRRRVFRQIIVKCVLQLLLIETTHELLQNERVYKTIP
PAELLRLMSALDESYRFARKFNADKELRMALWKVGFMRDLPNLLRQESTSAATLVNVLLR
MYSDPQEEAVQKRAEVVDVFAPLGLDVLANYVSLNPETQARNITAWTPVCTEILQGFRSF
EDEPFKAQLPRLYPLVTNTLVREADPALREAVRQVFIKVGTVSLGIKDEGDA