Protein Info for mRNA_1975 in Rhodosporidium toruloides IFO0880

Name: 10343
Annotation: K12350 SMPD1, ASM sphingomyelin phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 transmembrane" amino acids 83 to 102 (20 residues), see Phobius details PF00149: Metallophos" amino acids 242 to 527 (286 residues), 44.7 bits, see alignment E=1.2e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (777 amino acids)

>mRNA_1975 K12350 SMPD1, ASM sphingomyelin phosphodiesterase (Rhodosporidium toruloides IFO0880)
MPPPPSRPRLSLVSRLFRNPPSRQYASLHSPDIELAELEHPSDVAATKDGALSKPRPFFP
SLPVSLIPRQTEHKHHHFSKCDVFVTTLVLAILALVVVAFALSENPAVTFVETAASCTAC
ATALAPLKILAQAGDDAFTGVIVEFCIGSAIADPDVCRGAIGSQAPILAHSLRSLSVHLP
GATRLCTNVFGLCPITAVVPHKVDLPPESLAVSSHEFTRRTKLGETGLRRRWEDEAHDGE
TFQVVQISDVHIDKEYLVGASDDCTKPICCRDYGPSSTGPDVKTPAEQFGNRRCDTPQAL
MDNLLAAVEQIAPNRSFTVFSGDVIDAAVWDATEERVLNGLHDFSDGLASWGHSANSISE
TTSAEKPIYPVLGNHDIGPGNAFALDSTINAASATNAQQIYNMSASDWRRWIGDDAVNQV
QTNFGCYSVVHPGTNLRIISLNMNYWSEQNYWLYASDWPEWDPNGIITWLASELEAAEKA
GQRAWLISHSPPGRRDIFREQSNYVYQIIQRYRHTIAAQLYGHAHWDEWELGYEDPTKPS
SESAIAVALLAGSVTPRSGDPVFRVYDISKTTYEVLDFTVYHADMFAPGYQQGPSWKPFY
SARDYNQFLDPPFPPNAALNATYWSLVTDALEQNDSAWDAFEKYDAHGAWGRGCNGNAAC
RKEQLCILRAMRSEDSCEVIRPGFALNKRDLNRLSLSAIVISRLWHWQSFQDEHACEGPG
LGMLLRQVGAEARAAGAKDSLAGPGATRPRTLLSVLHRQAEAAVHRHRLSKKRWWRV