Protein Info for mRNA_2040 in Rhodosporidium toruloides IFO0880

Name: 10408
Annotation: K11729 ACAD10 acyl-CoA dehydrogenase family member 10

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 PF02771: Acyl-CoA_dh_N" amino acids 36 to 152 (117 residues), 41.3 bits, see alignment E=4.5e-14 PF02770: Acyl-CoA_dh_M" amino acids 157 to 255 (99 residues), 63.4 bits, see alignment E=3.8e-21 PF00441: Acyl-CoA_dh_1" amino acids 272 to 425 (154 residues), 109.8 bits, see alignment E=3e-35 PF08028: Acyl-CoA_dh_2" amino acids 289 to 406 (118 residues), 46.5 bits, see alignment E=9.6e-16

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 63% identity to uma:UM06400.1)

Predicted SEED Role

"Butyryl-CoA dehydrogenase (EC 1.3.99.2)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases or Butanol Biosynthesis or Isobutyryl-CoA to Propionyl-CoA Module or Isoleucine degradation or Valine degradation (EC 1.3.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2, 1.3.99.3

Use Curated BLAST to search for 1.3.99.2 or 1.3.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>mRNA_2040 K11729 ACAD10 acyl-CoA dehydrogenase family member 10 (Rhodosporidium toruloides IFO0880)
MDNSHPVVPYIGQAAWAFVQPHFSQYGKDTLAKLIAFVEGECIPAEKLFHDQISTDPLTR
WKSYPAVIEQLKQKAKDRGLWMLWANKAQYQQIGNGLSNLEYAVMAEIMGHAIRVAPEAT
NSSAPDTGNMEVLARYGNDAQKRQWLQPLVEGKIRSSFAMTEYGIASSDATNIRTSIVLD
EKTNEVVINGHKWWISGAGDPRNKVHLVMGKSDPKANKYNQQSIVIVPSDTPGVKLVRPM
QVFGYDDAPEGHFEVKYENVRVPASNLILGLGRGFEIIQGRLGPGRLHHCMRSIGLASRA
LELALLRATDERKQTFGKSLYQHGTVVRDIAECRIKIDQARLLVLSAALVVDKHPERAKG
ALREIGMAKAFVPTVVNEVIDRAMQLHGAEGICQDTPLAQMWAGVRTLRYADGPDEVHLD
QLGRTELKKVPEIRAKHERFRKREEEVTKGEKTASKL