Protein Info for mRNA_2134 in Rhodosporidium toruloides IFO0880

Name: 10502
Annotation: K10660 MARCH5 E3 ubiquitin-protein ligase MARCH5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 transmembrane" amino acids 175 to 200 (26 residues), see Phobius details amino acids 220 to 238 (19 residues), see Phobius details amino acids 245 to 264 (20 residues), see Phobius details amino acids 277 to 295 (19 residues), see Phobius details amino acids 426 to 450 (25 residues), see Phobius details amino acids 517 to 536 (20 residues), see Phobius details PF12906: RINGv" amino acids 98 to 148 (51 residues), 29.7 bits, see alignment 2.9e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (592 amino acids)

>mRNA_2134 K10660 MARCH5 E3 ubiquitin-protein ligase MARCH5 (Rhodosporidium toruloides IFO0880)
MLPSQQVPRRPAQDPYRYSSASDDSESATSSVSAQHPAHHPLDAEEDGGEPVREDLQAND
EAGRTQERAERRHDPVRLASPRPPQRTVSIDTAGERTCWICYATSTEEPNRPFIHACSCT
LLAHPDCLLQWIQTQAAMQAQAPRCPVCATPIVIKEKRSEALRLYKKVRRNLDQVSLVAA
VGSLAASGWFVAAAYGAWAIKVFFGDQVTQALLLRHENGLPWRYAVNLPLIPLTLVLSRT
PLIDSLLPFLPLTLILSTHTHTPLFDPIGLDDLTLRWPPSPTLTVCLLPWLRIFYFRLRT
KVFDAVLGKKKRFRGLAGVFEEAAEDELATVDTNEQPRREIMGVVATFELDVEAETARRA
AAPTTQAEAATQPNGPQMDGQTEQHEDNAPAPPYAEIQPAQHEQDGEEQGVQPDLLRLRV
GLGRLTSIVLGALLFPALSSLAGSALYFLASRHSSARPFRLLRRILGISADIAASRTSAT
ASRAGSVLGLGWIRQLTSAGSALRAAPMDPRWVRNTIGAGLVLLVRDAFELTAGVLEKRR
KDSRRIVERPFRPSSGATRASEPRRGSEGTAAATSSGGRDRQGREAVVHNFL