Protein Info for mRNA_2209 in Rhodosporidium toruloides IFO0880

Name: 10577
Annotation: K14157 AASS alpha-aminoadipic semialdehyde synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1012 transmembrane" amino acids 940 to 958 (19 residues), see Phobius details PF05222: AlaDh_PNT_N" amino acids 55 to 180 (126 residues), 71.1 bits, see alignment E=2.4e-23 PF03435: Sacchrp_dh_NADP" amino acids 529 to 660 (132 residues), 55.9 bits, see alignment E=1.1e-18 PF16653: Sacchrp_dh_C" amino acids 665 to 988 (324 residues), 261.7 bits, see alignment E=2.5e-81

Best Hits

Predicted SEED Role

"Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR) / Saccharopine dehydrogenase (EC 1.5.1.9)" in subsystem Lysine degradation (EC 1.5.1.8, EC 1.5.1.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.1.8 or 1.5.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1012 amino acids)

>mRNA_2209 K14157 AASS alpha-aminoadipic semialdehyde synthase (Rhodosporidium toruloides IFO0880)
MRGDTPRPRYLARLFSTAYTMQSVSLARTRFARQLRTKGRPFSGSAQALAVLGLRAEDPA
RKWERRAALDPEAVSELVKDGHDVLVEKCAKRAIGNDEYAKAGARVVDAFDPSACDVVVG
VKEPTIPSLSSNTSLSKPAAHLAFFHCHKGQEYNYPLLRTLLQSSKRSGTRFIDYELLTS
CSGTPTRSEPTIPGTSITPPTAPPRKRTVGFGFLAGCSGMADGLAQLGTKLLAGKGVVSP
FLSLPRPLQAGTVDRMEKELRRVGEAIRRGEMGERLGPIVITISGRGKVGDGARKALDEL
GVEWVKADKLPEVASHAPTTIYACHLELSDYLVDRSGKAFDREEYRAHPERFDSVFHEKV
APYSTVFLNGGFWAPPSPRLLTTAQLAALQQSPKSRLISIVDVSCDFGGGLEFVKAATTL
DDPIVQYDAVSDQLHRDPAHPTSIQLSSVEILPSAFPLDATKHFSKVLLPYLRHLLDDPS
LARTTGDSEIREALKRATLVRDGKLEKQHEWLYGVLEKANVAEKRRKAVLLGAGLVAGPA
VRTLAARPDVDVIVGASRFKAPEDDANSFARTASNDLPAAEKLASGLANVSTVSLDASSE
QALSDLVASADVVLSLLPAPMHVNVANLCIKHKKALVTASYVSPAMAALHDSAKDAGVVL
LNELGLDPGIDHITAMRLIHEAKETGNKIKSFVSFCGGLPAPEISNVPLGYKFSWSPRGV
LTAALNSASFRLSGRNISIPGSDLLRLNFPQVPLIRGFAFEGVANRDSLAYLPQYGLDKD
LPTILRGTLRYPGFSKIADAFKRLGLFDTEALDAPVERWTDLLPVCLRKQGFTVDAGLQS
ALEQVLGGDAALAREVFQELQALSLVEGADSSLASDLPPLPSVPAAPIDLLSGILANRLA
YKPGERDAVVLAHQVTTESADGQVELFTSSLVQYGDEKASAMATTVGVPIALGALLYLDG
KIAQRGVVSPASDEVWRPMLTALQDAGIRFVEGRRKGTRGVLEQLEQQVARF