Protein Info for mRNA_2385 in Rhodosporidium toruloides IFO0880

Name: 10753
Annotation: K01885 EARS, gltX glutamyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 835 TIGR00463: glutamate--tRNA ligase" amino acids 192 to 714 (523 residues), 543.7 bits, see alignment E=2.4e-167 PF00749: tRNA-synt_1c" amino acids 216 to 520 (305 residues), 354.7 bits, see alignment E=3.9e-110 PF03950: tRNA-synt_1c_C" amino acids 523 to 712 (190 residues), 117.5 bits, see alignment E=6.3e-38

Best Hits

Predicted SEED Role

"Glutamyl-tRNA synthetase (EC 6.1.1.17)" in subsystem Heme and Siroheme Biosynthesis or tRNA aminoacylation, Glu and Gln (EC 6.1.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.17

Use Curated BLAST to search for 6.1.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (835 amino acids)

>mRNA_2385 K01885 EARS, gltX glutamyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MASANTPILRLQAKSSPIPLGLCAFAYSLPPAQIQLEWVHSLPKEANGANCQVEINGKSV
FGTVECFKALGDAFAAQGALGKDNKESTEILSLLLLAPPFPPSFPTATSFLSTLEQRLTL
RTYLTGSSHPTVADYHLWAALKTNVIAIGLLPKAPHTQRWFNHLAALPPCAKALVDVPAQ
SKVKPAPAADKKDEKKKEEKANATFELGLPGAQKGKVVTRLPPEPSGYLHIGHAKAAVLN
QYFARMYDGKFLVRFDDTNPSKEKAEFEQSIVEDLALLGIKADATSYTSDYFDQLQQYAI
QLIKDGKAYADDTEQEVMRDQRMNGVASKRRDLSPEESLAKFAEMATGSDEGKRWCIRAK
MSVDDPNKALRDPVIYRVNDLPHHRTGSKYKIYPTYDFACPVVDSIEGVTHALRTNEYRD
RNPQYQWMLDAVGLRKVDVWDFGRLAFVYTLLSKRKLKWFVENGYVSGWDDPRFPTVRGI
RRRGMTVEAITQFMLLQGPSQAFLNLEWDVIWNLNKKVIDPVAPRFVALEKENLVPVKII
GGEGKPAEGQVESKVVPKHKKNPEVGDKTTFYADTIYVEQADAASFAQDEELTLMDWGNA
FVRKISRSSDAGPVTSLEMELNLAGDFKKTKKKVTWLGSPKAPSSPEDLTQVSLLDYDYL
ITKKKLEEDDNVEDLINPKTEYRTDAVADHNVASLAQGTIIQLERKGFYIVDRAFDASNP
SQKVELILIPDGRASSVALKHQAPAAPAKDASKAAKTPSKDKQAAMKAKKSTEAIPQLPE
LAPAEAVEVVLKSDGSRGYNIPVKTKMYKVDSPHGHEAYETPTTTSMYEMRPINE