Protein Info for mRNA_2414 in Rhodosporidium toruloides IFO0880

Name: 10782
Annotation: KOG1185 Thiamine pyrophosphate-requiring enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 transmembrane" amino acids 479 to 499 (21 residues), see Phobius details PF02776: TPP_enzyme_N" amino acids 11 to 181 (171 residues), 121.3 bits, see alignment E=5.1e-39 PF00205: TPP_enzyme_M" amino acids 217 to 347 (131 residues), 38.9 bits, see alignment E=1.1e-13 PF02775: TPP_enzyme_C" amino acids 434 to 598 (165 residues), 65 bits, see alignment E=1.1e-21

Best Hits

Predicted SEED Role

"thiamine pyrophosphate enzyme"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (603 amino acids)

>mRNA_2414 KOG1185 Thiamine pyrophosphate-requiring enzyme (Rhodosporidium toruloides IFO0880)
MSPTAPVEVYTTSNVLLDSLVEAGIKRAFVNLGSDHPALLEAFAHRKKYGLDSLEIVTCP
NEMVGLSAAQGYAQVTGKPAAVIVHVDCGTQALAGAVHNVSTCRTPVLIYAGASPYTQDG
ELAGSRNEFIHWLQNAVDQPQILRQYMRHVGEIRSGKNTKQVVNRALQFAKSEPMGPVYV
WGQREATEEHIDPASVPKVRKDIWSPVELSPLNDSSVARIADSLLRAKQPLIITSYLGRN
PLAVSALTSFVDLTSIPVFQPTLSTVNLPFDHHCHVGVAFGGRWEVVEEADVILIIDSDV
PWIPLHTKPREDAEIFHLDVDPLKERMAFASYPALLRAKTDAATALSQLHAYISSSPSFS
TSATKSAIDARRAELIEKHQKAMSELVKLEQVPSDGVMTSSFIVGMYRRLTEEMKVESLV
CNEAISNYPNVWNHIIPKRANSLISSGASSLGWALGAAIGATQGSHDFPSPSSAKNDLVT
VFVGDGSFIFGVPSAAYWMARRYETPFLTVVFNNGGWKSPKLSLLGVHPSGLGASGQTAD
LNVSFGPSDSLNPDYGAIAAAAGGAWCKKVLKAQELESAMREALRVVREEKRCAVLDCWL
SRF