Protein Info for mRNA_2476 in Rhodosporidium toruloides IFO0880

Name: 10844
Annotation: KOG0673 Thymidylate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details PF00303: Thymidylat_synt" amino acids 103 to 415 (313 residues), 235.9 bits, see alignment E=2.5e-74 TIGR03284: thymidylate synthase" amino acids 103 to 411 (309 residues), 167.9 bits, see alignment E=1.4e-53

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>mRNA_2476 KOG0673 Thymidylate synthase (Rhodosporidium toruloides IFO0880)
MTSCVPYPPSTDPIHPLIAAFAAGLLAGLSFSTSSPSPPPAPATASCGESDSSSSPRAHF
EAGTRASTPSTAPSTPASSLGSPSLESDAASLPYTSSALEETQYLKLAHSVIEQGELRSQ
VKGGTGARAIFAPDPLRFSLSRPVDPSNLFSPLENVIPLLTSKRMPFGVIREEFAWMVRG
ETNAKVLEVMGVKVWTENSSRDYLDSRGLEHLEEGDIGPAYGFQWRHAGAQYRGCEADYQ
GEGVDQLARLVRSLLETPQKRKHVLVAWSPADVDNMAVPPCPILHQFYLHEPVLSLLPVQ
PKPRLSCVVYQRSADICLGLPFDLVNAALLTHLIAHMTGSVADQLTYVIGDAHVYLDHEP
ALREQFARPLVHDFPTVSFARSREEIERDGGFDSIVGEDFKLGKYEAAPKLSFKLHP