Protein Info for mRNA_2820 in Rhodosporidium toruloides IFO0880

Name: 11188
Annotation: HMMPfam-2-oxoacid dehydrogenases acyltransferase (catalytic domain)-PF00198,HMMPfam-Biotin-requiring enzyme-PF00364,HMMPfam-e3 binding domain-PF02817,SUPERFAMILY--SSF47005,SUPERFAMILY--SSF51230,SUPERFAMILY--SSF52777

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 PF00364: Biotin_lipoyl" amino acids 2 to 37 (36 residues), 23.8 bits, see alignment 4.8e-09 PF02817: E3_binding" amino acids 90 to 124 (35 residues), 56.1 bits, see alignment 5.7e-19 PF00198: 2-oxoacid_dh" amino acids 156 to 447 (292 residues), 160.9 bits, see alignment E=5.6e-51

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>mRNA_2820 HMMPfam-2-oxoacid dehydrogenases acyltransferase (catalytic domain)-PF00198,HMMPfam-Biotin-requiring enzyme-PF00364,HMMPfam-e3 binding domain-PF02817,SUPERFAMILY--SSF47005,SUPERFAMILY--SSF51230,SUPERFAMILY--SSF52777 (Rhodosporidium toruloides IFO0880)
MSDKASVEITSPFSGKIASLAGAAGDMLKVGSVLCSIEVEGGEGEADSAPAAAEPAAPEP
APAPASSSTTPSSTTPSSSSSPSRSSNTEVLATPATRRFAREHDVDLSSITGTGRDGRVT
KEDIWKFVSEGPSAPSSAPAQASAPTATSTLTAPAESTTIPLNSTRKAMYRAMSASLQIP
HFSYSDVVDVTEIERMRLILASNIPLQYRKTLKPADEATLARQEQWTGAARVDPTRQFGR
ITLLPLLLKALSLAMSEHPIFTCTLSPPPSAGPATTDPSLVRRPTHDISVALSNPSPAGG
LFTPVLRSIDTSSVFDLASRLAHLQSLLPTSGNGAPKFPPEYQGAGTLTLSNIGVIGGRT
THPVVPPTGQLAIGAIGRTRVEPRFVDEARAKRVASGMEEAGAAELKVEPRLVMDVTFSA
DHRVVEGVELARLVESWKRIVENPARLAA