Protein Info for mRNA_3107 in Rhodosporidium toruloides IFO0880
Name: 11475
Annotation: K11412 SIRT2, SIR2L2 NAD-dependent deacetylase sirtuin 2
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"NAD-dependent protein deacetylase of SIR2 family" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Redox-dependent regulation of nucleus processes
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (416 amino acids)
>mRNA_3107 K11412 SIRT2, SIR2L2 NAD-dependent deacetylase sirtuin 2 (Rhodosporidium toruloides IFO0880) MSAPSSKPNRAFPHLTTSEKPTLEDVAKLIKDGKAKRIMLMVGAGVSTGAGIPDFRSPGT GLYDNLAKYKLPYSFTFRRAFDELQALIQQLTHFPFSPEAIFDVDYLEERPEAFYTLAQE LYPGNFRPTLSHYFFRLLQEKGVLRGCWTQNIDTLEHLAGLKDELLVEAHGSFATATCLN CRTKFDKDDIKPRVLRGEVVRHDEGKCKGNKRALIKPDIVFFGEGLPDKFFERLSDFSSC DLLIVIGTSLQVGPFNSLMHRVPATCPRLLINMESVGEVESPRGLGFDFTGFTGKPGGIR DVRRLGDADEGIMELARLIGWDEDLRELKEKEWKRLDEQEGKAAPAPAKADKEKAKEKAE EKRSEVIEQVEETVEANEGKKEDEAGVDELTKAVAGVALDGDTADTRKDEEKKPAL