Protein Info for mRNA_3311 in Rhodosporidium toruloides IFO0880

Name: 11679
Annotation: K00134 GAPDH, gapA glyceraldehyde 3-phosphate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00044: Gp_dh_N
  • amino acids 11 to 113 (103 residues), 96.9 bits, E=8e-32
• PF02800: Gp_dh_C
  • amino acids 187 to 352 (166 residues), 175.3 bits, E=7.5e-56

Predicted SEED Role

"NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)" in subsystem Calvin-Benson cycle or Entner-Doudoroff Pathway or Glycolysis and Gluconeogenesis or Pyridoxin (Vitamin B6) Biosynthesis or Redox-dependent regulation of nucleus processes (EC 1.2.1.12)

MetaCyc Pathways

• superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (20/22 steps found)
• superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass (22/25 steps found)
• Bifidobacterium shunt (14/15 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (11/12 steps found)
• glycolysis III (from glucose) (10/11 steps found)
• gluconeogenesis I (11/13 steps found)
• glycolysis I (from glucose 6-phosphate) (10/12 steps found)
• homolactic fermentation (10/12 steps found)
• glycolysis II (from fructose 6-phosphate) (9/11 steps found)
• glycolysis IV (8/10 steps found)
• superpathway of glucose and xylose degradation (13/17 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• superpathway of glycolysis and the Entner-Doudoroff pathway (12/16 steps found)
• gluconeogenesis III (9/12 steps found)
• superpathway of anaerobic sucrose degradation (14/19 steps found)
• Entner-Doudoroff pathway I (6/9 steps found)
• glycerol degradation to butanol (11/16 steps found)
• superpathway of pyridoxal 5'-phosphate biosynthesis and salvage (7/12 steps found)
• heterolactic fermentation (11/18 steps found)
• superpathway of hexitol degradation (bacteria) (11/18 steps found)
• pyridoxal 5'-phosphate biosynthesis I (3/7 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (11/19 steps found)
• superpathway of N-acetylneuraminate degradation (11/22 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of alkaloids derived from terpenoid and polyketide
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Biosynthesis of terpenoids and steroids
• Glycolysis / Gluconeogenesis

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.12

Use Curated BLAST to search for 1.2.1.12

Protein Sequence (391 amino acids)

>mRNA_3311 K00134 GAPDH, gapA glyceraldehyde 3-phosphate dehydrogenase (Rhodosporidium toruloides IFO0880)
MPHSTLPDVPRIGISGFGRIGRAVFRASLERDDLQVVAINHTAPNLRTFIYSIKYDSTHG
HLKQADELSVDEAKNCLYFRGRKIQLFSERDPLKLDWKSAGAEYIVEATGKHCTTATAGL
HLQSGGKKVVISAPAKDSETKTIVVGVNRKEYKPDMDVVSNASCTVRFPASRPRRSANLA
FLQTNCLAPLAKILHDTFGIEAGMMTTVHASTSSQPILDGYSKKSVRLGRGVGSNIIPTT
TGASKAVALVLPELAGKFTGLSVRVPVNNVSMVDLTVRLQRPAATKEDLLFPLREAAAGR
LKYSTGPISNVIAVNDEELVSHDFVGWQQSCIVDSAATIMLNPTLAKVVAWYDNEVAFSI
RMLDLIRYMYNVDNNLLASAAGTPASLASSA