Protein Info for mRNA_3364 in Rhodosporidium toruloides IFO0880

Name: 11732
Annotation: K15423 PPP4C serine/threonine-protein phosphatase 4 catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF00149: Metallophos" amino acids 46 to 237 (192 residues), 135.3 bits, see alignment E=2.2e-43

Best Hits

Swiss-Prot: 75% identical to PPX1_ARATH: Serine/threonine-protein phosphatase PP-X isozyme 1 (PPX1) from Arabidopsis thaliana

KEGG orthology group: K01090, protein phosphatase [EC: 3.1.3.16] (inferred from 78% identity to ppl:POSPLDRAFT_118560)

MetaCyc: 64% identical to serine/threonine-protein phosphatase 2A catalytic subunit (Homo sapiens)
Phosphoprotein phosphatase. [EC: 3.1.3.16]

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.16

Use Curated BLAST to search for 3.1.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>mRNA_3364 K15423 PPP4C serine/threonine-protein phosphatase 4 catalytic subunit (Rhodosporidium toruloides IFO0880)
MSSSLDRQIEQLKNCQPISEQQVKELCLKAREILVEEANIQWIDSPVTICGDIHGQFWDL
LELFRVGGQCPDTNYLFLGDYVDRGFYSVETFLLLLALKVRYPDRMTLIRGNHESRQITQ
VYGFYDECMKKYGSASVWRYCCEVFDYMSLGAVVDGRVFCVHGGLSPNVNSLDQIRLIDR
KQEVPHDGAMCDLLWSDPDDIEGWGLSPRGAGYLFGADVVKQFVHANNLDLIARAHQLVM
EGYKLMFEDKIVTVWSAPNYCYRCGNTASVLELDENLNSTYKTFDAAAQQDARNIPVKST
SLQYFL