Protein Info for mRNA_3425 in Rhodosporidium toruloides IFO0880

Name: 11793
Annotation: K00789 metK S-adenosylmethionine synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF04321: RmlD_sub_bind" amino acids 1 to 289 (289 residues), 193.8 bits, see alignment E=9.2e-61 PF01370: Epimerase" amino acids 3 to 218 (216 residues), 99.2 bits, see alignment E=6.7e-32 PF16363: GDP_Man_Dehyd" amino acids 36 to 214 (179 residues), 43.1 bits, see alignment E=9.7e-15 PF02719: Polysacc_synt_2" amino acids 42 to 182 (141 residues), 24.6 bits, see alignment E=3.4e-09 PF07993: NAD_binding_4" amino acids 60 to 183 (124 residues), 29.6 bits, see alignment E=9.8e-11

Best Hits

KEGG orthology group: None (inferred from 48% identity to pan:PODANSg8916)

Predicted SEED Role

"dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133)" in subsystem Rhamnose containing glycans or dTDP-rhamnose synthesis or linker unit-arabinogalactan synthesis (EC 1.1.1.133)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.133

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>mRNA_3425 K00789 metK S-adenosylmethionine synthetase (Rhodosporidium toruloides IFO0880)
MRVVVTGASGLLGRAVFAAFKEAGHDVKGTAYSRASGDLVKLDLQDEKAVEQFFADFKPE
CVVHCAAERRPDAVEADPEAAKKLNIAVPAYLSTLSRSSAHPFALIYISTDYVFDGHAPS
TGYEPDAETGPTNAYGESKLAGEEAVLEGLEQGGKGCVLRVPVLYGKAEKHSESAINVLV
DSVRKAAAGQSVKMDDWATRYPTNVTDIARVLVDLAAKSASTQLPHVLHFSAQQLYTKYT
ISLLFAKLHNPPLELGNNLVRVTEGPKPGETIRPKDCHLSNRAIEALGIDTRTIDFEQWW
TDYLRSEQA