Protein Info for mRNA_3639 in Rhodosporidium toruloides IFO0880

Name: 12007
Annotation: K11204 GCLC glutamate--cysteine ligase catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 784 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 468 to 490 (23 residues), see Phobius details PF03074: GCS" amino acids 262 to 705 (444 residues), 551.3 bits, see alignment E=6.7e-170

Best Hits

Predicted SEED Role

"Glutamate--cysteine ligase eukaryotic (EC 6.3.2.2)" (EC 6.3.2.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.2.2

Use Curated BLAST to search for 6.3.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (784 amino acids)

>mRNA_3639 K11204 GCLC glutamate--cysteine ligase catalytic subunit (Rhodosporidium toruloides IFO0880)
MGLLALGTPLVWSEAKKHADYVREHGIEQVLNIWERLKDRTGDRLLWGDEIEYLVISYDD
ANRNACLSLRQTEILQDLQADAEARRERGKDVVNGDGAAASGAGKEACIPVFHPEYGRYM
LESTPGAPYGATLEDLLLVEGNMRFRRKLAKSRMKPHEVPLTLTSFPRLGAPGQFTDPYY
PPGGGVARSLFLPDEVINQHVRFPTLTANIRRRRGSKVAINMPVFFDEKTPRPFVDPNVP
RDRNEWPEDKNAREGAALDDHIYMDAMGFGMGCCCLQITFQACSVGEARRMYDAFVPVGP
IMLALSAAAPIFRGLLADVDCRWDVIAGSVDDRTEEERGLKPLQHDRFLIPKSRYDSVDC
YIADTPFNRPEYNDNNMPIDPKIRDHLIERGVDPLLATHFAHLFIRDPIVIFEETMCQDD
AKSSDHFENIQSTNWQTVRFKPPPPGSPIGWRVEFRSMEVQLTDYENAAFSVFIVLLTRA
IMSLGLNFYLPISKVDENMHRAHRRDAINTQKFYFRKNVFDPKPGHPCDPSLDAAEPQPA
PSSDDATLPSASAFGRGRTNGFAAHVRDASVASSDYPASPTVCSSHAPSRSASPTPDIAF
GPVEDEYDEFSINEIINGSKEKGFPGLIGVVERYLDGLEKEGKVSEEVRKGIDRSLELIR
RRADGSLITLATYIRRFVRSHPSYAHDSVVSQEINYDLIRALDEIEQGKRPAPELLPEGW
RTGYDEDKKGKGAFGRCCGDVVGDVASDDAQSEGSEGLSAGAAVIEDKGLCCGPMEPAPA
AKEA