Protein Info for mRNA_3666 in Rhodosporidium toruloides IFO0880

Name: 12034
Annotation: K16055 TPS trehalose 6-phosphate synthase/phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 PF00982: Glyco_transf_20" amino acids 17 to 394 (378 residues), 480.3 bits, see alignment E=6.3e-148 TIGR00685: trehalose-phosphatase" amino acids 425 to 635 (211 residues), 173.6 bits, see alignment E=6.7e-55 TIGR01484: HAD hydrolase, family IIB" amino acids 429 to 630 (202 residues), 90 bits, see alignment E=2.3e-29 PF02358: Trehalose_PPase" amino acids 431 to 632 (202 residues), 227.6 bits, see alignment E=1.2e-71

Best Hits

KEGG orthology group: K00697, alpha,alpha-trehalose-phosphate synthase (UDP-forming) [EC: 2.4.1.15] (inferred from 52% identity to mgl:MGL_1326)

Predicted SEED Role

"Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)" in subsystem Trehalose Biosynthesis (EC 2.4.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.15

Use Curated BLAST to search for 2.4.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (733 amino acids)

>mRNA_3666 K16055 TPS trehalose 6-phosphate synthase/phosphatase (Rhodosporidium toruloides IFO0880)
MTTRELAACRFGWTTGCTRFYEGMCKEYLWPIFHYLSLPDNISKKTEQAAWDAYYETNLV
YARKVASVYKPGDLIWIHDYHLLLVPQMLRDLLPNQSPTISLFLHCPFPSSEFFRCLPRR
EQLLDGMLGCNLVCFQTHSYARHFLSSCVRVNGYEARAGGVDVHGRVVHLAHCPIGIDVD
NVEQDRNSPGVRPKIEALRRLYAGKKIIVGRDKLDPTKGVLPKLRAFERFLHDYPEWANK
VVLMQVTSPSPGDSPALATKVSELVDQINGTYGSLEFQPVHHYHQTIERDEYFALLSVAD
LALVTSRRDGMNTTSMEYIICQAEAKGSLVVSEFTGVSSLLSKAIKVNPWDLGGVARAID
SCFKMPLDERAARHNVLHRAVTSQTASVWAHMNILKLLESLQGEQATQNTPFLDENALVA
KYESANRRLLMFDYDGTLTPIVKDPSAATPSPQLLHSLETLAADPKNIVYIISGRDGAFL
EEHLGHIPNLGMSAEHGCFLRAPGSGKWVSLTDDLDMDWKADVLRIFRYYEARTQGAFVE
KKVSSVTFHYRNADPVFGLFQAKECQAMLESMQESLPIDVLVGKKNVEVRPAHTNKGEIV
RRLLYQHPDAEFCMCAGDDKTDEDMFHSMARIFSNSTPALGGSGKTLITPPESFALFPSL
AQAARASAPEGALPDDLSQPVESKLDPSATFMIAIEAKETAGAKMTMANAVLESPAAMIS
LLERLSDFSTSKQ