Protein Info for mRNA_3732 in Rhodosporidium toruloides IFO0880

Name: 12100
Annotation: K02541 MCM3 DNA replication licensing factor MCM3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 899 PF14551: MCM_N" amino acids 20 to 116 (97 residues), 48.3 bits, see alignment E=2.8e-16 PF17207: MCM_OB" amino acids 127 to 260 (134 residues), 120.7 bits, see alignment E=7.2e-39 PF00493: MCM" amino acids 301 to 518 (218 residues), 298.5 bits, see alignment E=4.6e-93 PF17855: MCM_lid" amino acids 594 to 677 (84 residues), 76.1 bits, see alignment E=4.8e-25

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (899 amino acids)

>mRNA_3732 K02541 MCM3 DNA replication licensing factor MCM3 (Rhodosporidium toruloides IFO0880)
MADFAGLPPLQDDQLATRTRRFTEFLDLDAGSEAAKRMSMHYRSSVKKMLDAQERRLVVN
LDDLRDYDREFCDGLLKEPAAWLPAADAALKDMAVNQAGDRMAESVKQDTFYVGFKGSFG
EHHTTPRTLRSDKLGKMVCMEGIVTRCNLVRPKMQQSVHYCPTTTNFHTRLYTDRLSSAA
ASGAPVSSSAYPQTDADGNPLEIEHGLSTFMDHQMISIQEMPERAPAGQLPRSVEVVMED
DLVDRCKPGDRLQIVGVYRSLGGGASGSAHFKTLIVANHVVLLSAKAGAGIAQQTISTDD
EREIRKVAKRKDVYELLWKSLAPSIYGSDYIKQAILLLLLGGVEKNLPNGTHLRGDINVL
MVGDPSTAKSQMLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMVLAD
RGVVCIDEFDKMSEVDRVAIHETVTIAKAGIHTSLNARCSVVAAANPIYGQYDVHKDPHK
NIALPDSLLSRFDLLFIVTDEADEQRDRQISEHVLRMHRYVQPGLEPGAPAVDSLEQHLS
VGTEQPAANAGGQAKTSPFEKYNELLHGGIAPKVVKKRGGKKETVPPDVLTIQFVKKYIQ
FAKSHVQPVLTPEASECITKAWTNLRNDDAGPNQKRTSPMTVRALETLIRLSTAHAKARL
SPDILIEDAEAAEEILRYALYKEVVKASKPKSKRRRLNKPKRGDKGSDEEDSDEDEGESS
SDDEDDGRGPKRMEMPGSAKKRGTRANPARGARAGSARAGSASPSPAAVEADGEGDWMMV
EQGQQRMNEDGDEQAAAGTPTPPPVPAVEQAEKVAQAELPAQGGLEPARFKLFQQRLAAV
RKATFKDQDEISLGQLMEPLNADLAVDQLFGRAEVEQILEALSEQDDSVITFHSGVLYF