Protein Info for mRNA_3864 in Rhodosporidium toruloides IFO0880

Name: 12232
Annotation: K08737 MSH6 DNA mismatch repair protein MSH6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1006 PF01624: MutS_I" amino acids 88 to 214 (127 residues), 112.5 bits, see alignment E=3.4e-36 PF05188: MutS_II" amino acids 223 to 384 (162 residues), 39.9 bits, see alignment E=1.3e-13 PF05192: MutS_III" amino acids 411 to 694 (284 residues), 120.8 bits, see alignment E=2.2e-38 PF05190: MutS_IV" amino acids 573 to 661 (89 residues), 36.3 bits, see alignment E=1.5e-12 PF00488: MutS_V" amino acids 749 to 937 (189 residues), 225.8 bits, see alignment E=1.2e-70

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1006 amino acids)

>mRNA_3864 K08737 MSH6 DNA mismatch repair protein MSH6 (Rhodosporidium toruloides IFO0880)
MARQTSLGGFGASARPQLKSAGSGSGGIGGIKTAAETAREKAKQDKQSNEEMFSFLVDPK
DIDGNRPGEPGYDPRTLYIPPAAWKQFTPFENQFWEIKQYHYDTVLFFQKGKFFELYEED
AAIGHREFDLKLTDRVKMKMVGVPETSFDFWAAKFLAQGYKVGRVDQCETALGAELRNKD
DKKAGKGKAKQAKGKEIVRRELKSVLTSGTIVDGSMLTDDMSNHCVAIKEHTPTPASAPS
FGVCVLDASTAEFSLSFFTDDASRTELETLVRQLKPKELIHQKGNLSVSTLRLLRNCLGL
ECQWTALKEGKEFLKAEDARDEVVKLFKESKKGGAGEGDEAEMEVDGADDENTVPESIRK
MYDKPVAMSALGGMIWYLRQLNLDADLVTARNFNIYDPLGRSNGTLVLDGQTLAHIEVLQ
NSQGTTEGTLLQLLSRCVTPFGKRLFKVWLCAPLRDATAINDRLDVVEDLLGNANFAVAF
DGMAKKLPDLERMLSRIHGKTCKKKDFIAVIEAFERIMTGLKTLGDLSEDFKSQGIPNLI
RSVPDISELLEEVQGLYIWDEEAGSLHPAEGKDEDFERVRQKVDDVEDELQQELRLVRKS
LKCPDVIFKHIGTKDIFQLEVPVKVKVPNNWTKMSGTQKVHRYYSPEIARLVAQLKEARE
RMQMVLYGEFDKHYTTWMAVIRAVSQLDCLLSLSKSSAALGEPCVRPEIVESDTAIVEFE
ELRHPCILSASTDFIPNDVVLGGDAKNLMLLTGPNMAGKSTLLRMACTAVIMAQLGCFVP
AASARIAPIDAIYSRMGANDFIFANASTFKVEMDDCNKILQKATPRSLVILDELGRGTST
YDGMAIAYAVLHRLATHTGCIGFFATHFTSLTEDFVYHPEIRLANMQTSVNDETREVVFL
YKLIDGSSPKSYGPHVAAMAGLSESIVERAIAISKQFEETSRARELAMRANETLPLTAQA
DAAFLIKLAKLKLADGKYMGDKKQLLRTLDVVRKAVGAIKETRAAA