Protein Info for mRNA_3889 in Rhodosporidium toruloides IFO0880

Name: 12257
Annotation: K00587 ICMT, STE14 protein-S-isoprenylcysteine O-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 55 to 77 (23 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 180 to 201 (22 residues), see Phobius details amino acids 234 to 258 (25 residues), see Phobius details PF07298: NnrU" amino acids 174 to 258 (85 residues), 23.7 bits, see alignment E=6.4e-09 PF04191: PEMT" amino acids 177 to 281 (105 residues), 45.4 bits, see alignment E=1.9e-15 PF04140: ICMT" amino acids 184 to 274 (91 residues), 81.8 bits, see alignment E=8.1e-27 PF06966: DUF1295" amino acids 186 to 288 (103 residues), 21.4 bits, see alignment E=3.3e-08

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>mRNA_3889 K00587 ICMT, STE14 protein-S-isoprenylcysteine O-methyltransferase (Rhodosporidium toruloides IFO0880)
MTEPLAAPESPFPPRPSPSSDPSSTQSSSSSGPTHAKPLPVEFPLTSFSSTPHNVACFAF
LLGACWAVGLVLVASNASTWFLWSLDAVKGAAGPLKLGERSLRTAVLGSPQLGAYLTSWA
AFHLLEFVVTSMYNPGKLSVSSFLLDNGRGYHAAHIAGILEHILEEAYLPEEWRRWKHAG
GLVVVWIGQVLRSFAMISASSNFSHLLAYSKRPGHQLVKTGIYSWSRHPSYAGFYWWAVG
TQIVLGNPLCTIAFVAVLQGFFANRIKIEEAYLVKFFGKDYEDYRRKVPTRILFIP