Protein Info for mRNA_3938 in Rhodosporidium toruloides IFO0880

Name: 12306
Annotation: HMMPfam-Dioxygenase-PF00775,HMMPfam-Catechol dioxygenase N terminus-PF04444,SUPERFAMILY--SSF49482

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04444: Dioxygenase_N
  • amino acids 71 to 141 (71 residues), 103.8 bits, E=3.4e-34
• PF00775: Dioxygenase_C
  • amino acids 150 to 311 (162 residues), 160 bits, E=4.6e-51

Best Hits

KEGG orthology group: None (inferred from 58% identity to cci:CC1G_09575)

Predicted SEED Role

"Catechol 1,2-dioxygenase 1 (EC 1.13.11.1)" in subsystem Catechol branch of beta-ketoadipate pathway (EC 1.13.11.1)

MetaCyc Pathways

• catechol degradation to β-ketoadipate (1/4 steps found)
• superpathway of salicylate degradation (2/7 steps found)
• catechol degradation III (ortho-cleavage pathway) (1/6 steps found)
• aromatic compounds degradation via β-ketoadipate (1/9 steps found)
• mandelate degradation to acetyl-CoA (1/18 steps found)
• superpathway of aromatic compound degradation via 3-oxoadipate (4/35 steps found)

KEGG Metabolic Maps

• 1,4-Dichlorobenzene degradation
• Benzoate degradation via hydroxylation
• Carbazole degradation
• Fluorobenzoate degradation
• Toluene and xylene degradation
• gamma-Hexachlorocyclohexane degradation

Isozymes

Compare fitness of predicted isozymes for: 1.13.11.1

Use Curated BLAST to search for 1.13.11.1

Protein Sequence (356 amino acids)

>mRNA_3938 HMMPfam-Dioxygenase-PF00775,HMMPfam-Catechol dioxygenase N terminus-PF04444,SUPERFAMILY--SSF49482 (Rhodosporidium toruloides IFO0880)
MSSAADQINQSTPRNAPKASPTASLLVGKAVKTALEQGAQNIDLSKLPNLTDMSPESITQ
NVHAINSLCEDPRQKFVFEKLVTHLHDFAREVSLTTDEWMNAIQFLTKVGQICSPIRQEF
ILLSDALGLSALVDSMNHPTKPPATEATVLGPFFTEDAADLSHGDSIASEGKGEYMYCEG
RVLDVDGKPVANCTIETWETDDEGLYDTQYSDRSHPDCRGRLHTDENGYYAYRLVKPTPY
PIPFDGPVGQMLKSLNRHVFRPAHLHMMFVAEGYETLITALYFKGDPYLTSDAVFGVKSS
LVVDTELIEDDARAKQLGFKHGPFHYLKKDYVLMTKDQAEEEKKKSLANYYKSIQP