Protein Info for mRNA_3982 in Rhodosporidium toruloides IFO0880

Name: 12350
Annotation: K19525 VPS13A_C vacuolar protein sorting-associated protein 13A/C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 500 1000 1500 2000 2500 3211 transmembrane" amino acids 2997 to 3012 (16 residues), see Phobius details PF12624: Chorein_N" amino acids 3 to 116 (114 residues), 124.3 bits, see alignment (E = 8.2e-40) PF16908: VPS13" amino acids 140 to 370 (231 residues), 267.1 bits, see alignment 5.2e-83 PF16910: VPS13_mid_rpt" amino acids 628 to 869 (242 residues), 316.7 bits, see alignment 2.7e-98 PF06650: SHR-BD" amino acids 2276 to 2550 (275 residues), 228.9 bits, see alignment E=2.4e-71 PF16909: VPS13_C" amino acids 2807 to 2981 (175 residues), 218.6 bits, see alignment 1.6e-68

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (3211 amino acids)

>mRNA_3982 K19525 VPS13A_C vacuolar protein sorting-associated protein 13A/C (Rhodosporidium toruloides IFO0880)
MVLEGVLAGILNRTLSAYVDNLNTSQLNVGIWSGDVKLRNLRLKKEALDKFRLPVDVVEG
YLGDLTLSIPWSNLSGKPVRVLIENVYLLAVPTDSSKATPEEDAARAQAAKLEKLENAEM
LTTHPAPGLSAEEEQKNQSFTTSLINKIVDNLQIEIRNIHIRYEDKLSVPGHPFSVGLTL
SRFSAVSTDENWQPTFITKHAGPVHKLATLDSLAVYFDTDSPSLAGHELSEAIVQFTDLI
AREGHTPSHQFVLKPVSGQGRLVMNKKVDAHTPKTDAELLFQELGFVLDADQYRDALSMV
DLFHFYIRQREYRSFRPPQEEFEKNRNRALWKFATSAIRSEVHEKHRQWSWEYFAERRND
RKAYVELFKKKTLGTIDVEESQELVDLEVKLGYKDIRFYRSIARSEMRKDRIEHPPPPKP
QTTTAKATSWLGSWVGWGGGGSAAAADQHESDDPSSGLNEEQRKELYKAIDWDEKDAVAN
AVDYPADTLLLRVKAKLETGSFALRTDPHGAAKNLIALNFDDLRLDMAQRPENLEATLAL
GGLRVFDGTCENTLHEQVVRVKEIAADEEEQRRAKKKQRARLPPPEEREADDDVGQYEDG
DEEVEDEIARDGVGEWAMQENPFFSLKFEHNPLDKRADNALAVRLRHTEIVYHRGYVEAI
FAFFQPPESQLESVGALIDVASETLEGIRKETRAGLEYALQQHKTVDVQLDLNAPIIIIP
ESMTQKDCQHIVLDAGHISVVSELADQSAIDAVKAKEHQEYQEEDYKRLESLMYDKFYVK
LEDAQLLMGPSLQTCLDALDVKGDHHSSSTGELHILERTSLTFLAQNCILAQAPNLTRFK
VSGSLPTLQLNFSDRKYKSLMRMIDVAIPHFGDEDVQVQRPGPQPNQRGTSFAQSRSRAA
TLDDDDEDLHVGHETDSEGAEGDIGDDEDDKDGGKDEFFDTPDIADGKQNIHQKTFEFSF
SVDRVQGSIYRSNADPTKPDRLLVNAVLEGFKVGFELRPYDMSVDVVLRSLYLEDKMTAA
QNSDFRHLLTSEKLEGGHEHDLVRVRYHGVQKNSPEFMTVHEGFDKSVDVEMSTLNLVVT
RSSILLLFDWIMTTFTDPVDISAPSSPQIEGAESETQVAEVNMDKLRVKVKLTSINLILN
EDGLRLATLSLSAADVSVLLRGPTIRVATHLGNLSLHDDFSSSTPQEMLTIQGDEFADFR
YETYDPNDKTTYPGYDTSVHLRSGSLRFTFRSEPVHRILAFFTKFGRMKAVYDAATQAAA
QRATEMQTMIPKMHYDILVKTPILVFPHEEAERADDTIVAKLGELSLKNDFEVTDEIVKT
KINFGLHEVGLESTLYHGGEAHSLPVLDGVRIDVSVTLHESVDPAKDLDAPGTLVSAKMS
DVKMKLTQAQYGLLIHLSQTIPSAFAFDEEELDDEASAMIEAAPVPSPPKKDVEAAVKGK
NGDVVRDEHGAEVVDLLPELPKSAKTVDGEQVQLKSTLEVDFAVNTVFLELFTEAATSTE
SLEEASLARFALNDTAVKYKMVSNGSMEAEVAIRSFTIHDTRPARLTKFREIIPATKHSG
HQFMVHYTQSGGLDKSAIANVTVDSPKIIFSLDPLFALVDYFSSAFPQAPNAGQDEDDID
EGLKEADEQKVDPSPATESTLAYRINVVSPTIILLENPAKADSEAVVLSLSQAQMTQQGT
LALTIARMGMFLCRMDRPKENIRVLDDVDVILSMDSRTDGGRQVTNIEVGVQPLILRVSL
RDIFLINSIINRAIELSNRGSPAPEEQPARPDLESLQSGKVRTRSKSNAATRRRSVSGAS
RPVREDLVKAQVIVTKETLRATFDGLQLIIIGDMHDLPLLDLKAGKFTAKAKDWSTDLDA
SVMIKPFINYFNLKVSHWEPLMDPWEFGVHVTRSVTTGLLAIDVSSKKRLELNVTSTFIE
VAMTTMSIMDREGDKVFKKPRGSNAPFLIKNRTGYPLSLWSESADAGARGQRLDDGDDVP
WRFDDWRTARENVSASTHNSLTVVFDGMGWERLKHVYVDREGEHIHALRPKIDKVTHRLL
CDVKLVDNVKVVTFRSTFLIENKSLVNAEMVIVDEHGKKASQVYKIPPGGECAVPILAAY
HNRIKLRPDPGFGYNWSTDSLHWQDLVKRPTRAIVCKSQKEAAFRFQAYALHDKSDPLVR
IYPKITLRLRAPVEVQNLLPHDVRYRVFDKNLEHNWTSFLRAGGVSPIHVAELSHLLLLS
VEVQDTNLGRSEFAIINTDNPEDLPVEGDLVLADKEDRKLNLRIHYQKHPDSGGAFRVQV
YSPYVLINKTGLPFALKTKSFFGSAKSVAGLDEFSSEAAKRKAEDAFMFSFPTDDRRNRA
LLRVGDSNWSAPLSFETIGLTTEVVLPSTTGKEEVRVGLKVTEGLGDYKLTRVITLCPRF
IVKNNFDEPIRVREFGSSEESLLQAGERHHVGFLRSGQAPQLSLSFPGSHHWSAPFKLQD
VGQNYVRVPISSSDERLARIDAVLEGPCIFVRLDPEQGAWPFLLRNDSDYPIDFWQAEHD
GVQGDGERNKRRRYRLERGSKLPYAWDRPADDIRQFRISCGGRERAVNPLEIGALIPFRF
NHEGHTAVISIDVRAEGSTQAVTFSNYVEEDSVFKLQRRNTETISRAESIASSRDAVFEA
VDVDVVTTFSLSVNLEGIGISIVNRKMQELIYASFRGVTAKYADSTTNVAYDVGIKWIQI
DNQLFGGLYPILLYPSVIPKDSKELEVHPSLQVSAILLKDEAHGVSYFKYASILLQEMTI
EVDEDFLFALLDFAKFSGANGMAEQESKLTEDPEEIPEPTATSKGGDLYFEVLHLHPIQL
DLSFMRTDRVNVEQKLNSHNPLYFFINALTMALGNVNDAPVRLNALVIENARLSLPVLQE
RLTVHYSDEFFGQLYRVLGSADVLGNPVGLFTNVSSGVADFFIQPYDSIMMNGNKDLGIG
IARGAGSLAKKTVFGLSDSLTKISGSIGKGLSAATLDKQYQSQRRMRQFRNKPKHALYGV
TAGATSFVTSVASGFEGLATKPLEGAEKGGAAGFFKGVGMGLVGAVTKPAVGIFDFANNV
TEGIRNTTTVFDQTGIDRVRLPRFTASDGVLRPYSEREALGQNWLKNVENGRYFSETYVA
HLDLPSSDDTLVVILTTTRILLVRVNKLKVGWDVPISDLATISLEASGITLVLRGSVPGP
FLAIPDQSARLWLFRHLERIVQAHNARRLVE