Protein Info for mRNA_4008 in Rhodosporidium toruloides IFO0880

Name: 12376
Annotation: K03695 clpB ATP-dependent Clp protease ATP-binding subunit ClpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 910 PF02861: Clp_N" amino acids 15 to 38 (24 residues), 12.5 bits, see alignment (E = 9.6e-05) amino acids 100 to 150 (51 residues), 36.1 bits, see alignment 4.1e-12 PF00004: AAA" amino acids 208 to 341 (134 residues), 49.6 bits, see alignment E=4.1e-16 amino acids 620 to 737 (118 residues), 34.2 bits, see alignment E=2.3e-11 PF17871: AAA_lid_9" amino acids 347 to 448 (102 residues), 108.2 bits, see alignment E=1.3e-34 PF00158: Sigma54_activat" amino acids 613 to 719 (107 residues), 22.5 bits, see alignment E=5.8e-08 PF07724: AAA_2" amino acids 614 to 780 (167 residues), 147.8 bits, see alignment E=2.5e-46 PF07728: AAA_5" amino acids 619 to 740 (122 residues), 34.1 bits, see alignment E=1.8e-11 PF10431: ClpB_D2-small" amino acids 786 to 868 (83 residues), 78 bits, see alignment E=3.4e-25

Best Hits

Swiss-Prot: 54% identical to HS104_SCHPO: Heat shock protein 104 (hsp104) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 60% identity to scm:SCHCODRAFT_73165)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (910 amino acids)

>mRNA_4008 K03695 clpB ATP-dependent Clp protease ATP-binding subunit ClpB (Rhodosporidium toruloides IFO0880)
MDKLTDAAIASVQAAIELAKENQQGTVAPAHLFSALLSPTTNATGQTQQTLLHSILNKAG
AQPELVARGLAKFIVRLPSQEPPPDDVSVSPALSKVIREAEKLMKEKNDSFVAQDHLILA
CIQDNSIINVLKEAGTTPDAVKKAAQQVRGGKQVNSKGAEEGFEALKKYAVDLTAQAEEG
KLDPVIGRDDVIRRCIRILSRRTKNNPVLIGDAGVGKTSVAEGLAQRIVNRDVPPNLIAR
IFALDLGLVTAGASYKGQFEERVKAILEECEKSEGSVILFIDEVHLIMTGQGSSGGGMDA
ANLFKPAMARGKIRVIAATTLKEWRIIEKDPAMERRFQQVIVNEPSVPETISILRGIKEK
YEVHHGVTILDSALVSAATLAHRYLTARRLPDSAIDCVDEACSAVRIARESRPEEIDKLE
RQKLQLEIELHALQTELARDKKDEVAKQKIEDTKQAISKIDDELAPIVARFEAEKSKGDE
LNRIRKRIDELTAKAADAERRYDLATAADLRHYAIPELQTRLTQLEEQKQAEERQRRAEG
AESLAGDTVTPEAIQQVVAQWSGVPVSNMKMTEKQKLLKMEKTLRKEVVGQDEAISAVAN
AIRLNRSGLSNQDRPIASFLFVGPSGTGKTQLAKALAKFLFDSPDAMIRLDGSEYSEKHA
IARLIGSPPGYVGHEEGGQLTEYVRRKPYTVVLVDEIEKASREFCQLFLQVLDDGRLTDS
QGRIVNFKNTVIIMTSNIGSAFLNELGDDVETVPPATRELVNGALRAALPIEFINRVDSI
IIYNRLSRKDVRGIVNIRLAEVQKRLRSNGRDITLSVSEPAMDFLGSIGYSPMFGARPLN
RAIQTELLNPLSKMILDESVRDGETARIEFDDKRNRLVVVPNHEPSVRMDEDEDEDMSGG
SDIEIEEVDD