Protein Info for mRNA_4014 in Rhodosporidium toruloides IFO0880

Name: 12382
Annotation: KOG0065 Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1483 transmembrane" amino acids 414 to 438 (25 residues), see Phobius details amino acids 445 to 465 (21 residues), see Phobius details amino acids 488 to 517 (30 residues), see Phobius details amino acids 527 to 549 (23 residues), see Phobius details amino acids 558 to 577 (20 residues), see Phobius details amino acids 670 to 694 (25 residues), see Phobius details amino acids 1140 to 1161 (22 residues), see Phobius details amino acids 1173 to 1194 (22 residues), see Phobius details amino acids 1215 to 1241 (27 residues), see Phobius details amino acids 1248 to 1274 (27 residues), see Phobius details amino acids 1283 to 1304 (22 residues), see Phobius details amino acids 1405 to 1425 (21 residues), see Phobius details PF00005: ABC_tran" amino acids 147 to 242 (96 residues), 32.2 bits, see alignment 2.2e-11 amino acids 817 to 965 (149 residues), 74.9 bits, see alignment E=1.4e-24 PF01061: ABC2_membrane" amino acids 398 to 608 (211 residues), 129.1 bits, see alignment E=2.5e-41 amino acids 1120 to 1331 (212 residues), 114.7 bits, see alignment E=6.3e-37 PF06422: PDR_CDR" amino acids 621 to 709 (89 residues), 69.2 bits, see alignment 3.6e-23

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1483 amino acids)

>mRNA_4014 KOG0065 Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily (Rhodosporidium toruloides IFO0880)
MDPLPHGLPLRFHSLEVPDPGGRSGGDSLVDDLANSFVDTATLGPLRRAFSSVRGRGKGA
ERAKVLVGGVEGVVHQGELLLVIGPPTSNASILVRALSCCSDLPLSSSSHLDYGLVDYSH
ANRPTLTSSLAQSGAGERNLRSQVVFMDDRDVHFASLSLEATLKPVSHAKTPEHRQDGST
RREWAEAKMGSIVEAMGLSHAYTTAVGSPLVRGLSGGERKRASLAEVLLTRAAILLLDGP
FNGLDSSTALSMLQYLRTWATSKRRSVIIATPHCADSLYEEFDKVLVLDARGRQVFFGRT
ADAQPYFERIGFKRRTDLGEGTAEFLVGCIEGRHNDVELERRWKASTERKALFHEIEEVY
PQRYPLSTCADPLFTALRDEKSRFTPASSHYTVSFPRQVVHLTRRQYALIRSELPAYVTK
TLINLLLSITVGTLFFRLPPVTEHAFTRGSLLLLSIMFNAYLSLAELGKTIEGRDIVKRQ
GDYGFFSASALAVARVAGDIPLIGVQCLLFGTITYLLAGLQPSLERFLIYLIFVYATALN
LSCLFRMVAAFSPGFEGAIRFCGVALNVLVMYAGYFIPTPSMRPWLKWIHYVVDPISYSY
EAVLANEFHGLRLDCSQADIIPSGPLYDSYAATFKTCSLPGSKPGSLTVLGDSYLSLTYD
FSFARIWRNLGILALQAAVFLVVGVVATEFLSFAEGGRRRVWKRTKAVKRRLFGAKQEKF
AYKDANGSGTAVNGARRPSEEERRLIEVDESGDEAGWDVEAQEEEAFEESSVVETPAYGS
DAEDENGATGEQIEGSVLAWNAISLWVDTPLETRRLLDRVSGYIKPGRVCALLGASGAGK
STLLNVLAGRSIGVVRGTIRVDGSEPDAEFYRTTGYVEQFDLHDDRSSVREALEFSALLR
QDASIPDSEKLAYVDHVLDLLDLTHLQDAIIGTPSAGLNAEQRKRVTIAVEVVSRPAILF
CDEPTTGLPTKSALRVVKLLRRLARTGLAVICTIHQPSAETFSIFDDVLLLQRGGKQVYF
GPRKDAVRYFTPAAKSDLASDIFVNPADFLLDVTKTGVDVPDEELNDVHDLDLLAKKWTS
SQEYGAVKAELVRLGAPLRQTKATEIIRKAPPPASSVWRQCVLLTKRVSKHYYRDPSFSY
TKLFTSTIVPAIIGLSFFLVGHENTIVSFQNRMFSVFLLLFVPVVWMNAIIFKVHSLRGL
WEARERPSRIYGRTAFVTSLLVSEIPYSLLCATTYFVLWYFLVGFPLKAATIAFAFLLIQ
IFYFFQSTWALWIVSLSQSLGTVANLLPFFLVAMEAFNGSLMPYAQMPRAWRWLYYVSPF
QHYIRSMLGGLLHDTPVRCAEYEVVSFRPPPGLSCEAYSADYLSRHAGYLLNPSSTSLCD
FCPMSTGDDFLASLNISHSDRWRSLSILAAYCVSNLAITYLLIFFPPRMPAWASRIFRRS
SSGGSGGRKGAEEVAAEHWAKELQFEREHPEAHAHPVAYDPFS