Protein Info for mRNA_4060 in Rhodosporidium toruloides IFO0880

Name: 12428
Annotation: K01537 E3.6.3.8 Ca2+-transporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1014 transmembrane" amino acids 184 to 202 (19 residues), see Phobius details amino acids 208 to 224 (17 residues), see Phobius details amino acids 378 to 397 (20 residues), see Phobius details amino acids 406 to 432 (27 residues), see Phobius details amino acids 804 to 827 (24 residues), see Phobius details amino acids 834 to 856 (23 residues), see Phobius details amino acids 877 to 897 (21 residues), see Phobius details amino acids 912 to 931 (20 residues), see Phobius details amino acids 943 to 963 (21 residues), see Phobius details amino acids 973 to 992 (20 residues), see Phobius details TIGR01522: calcium-transporting P-type ATPase, PMR1-type" amino acids 128 to 1002 (875 residues), 1117.2 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 131 to 199 (69 residues), 42 bits, see alignment 1.8e-14 PF00122: E1-E2_ATPase" amino acids 239 to 437 (199 residues), 161.4 bits, see alignment E=5.1e-51 TIGR01494: HAD ATPase, P-type, family IC" amino acids 358 to 476 (119 residues), 86.5 bits, see alignment E=1.4e-28 amino acids 712 to 832 (121 residues), 100 bits, see alignment E=1.1e-32 PF00702: Hydrolase" amino acids 454 to 758 (305 residues), 74.9 bits, see alignment E=3.4e-24 PF13246: Cation_ATPase" amino acids 511 to 589 (79 residues), 30.9 bits, see alignment 7.2e-11 PF00689: Cation_ATPase_C" amino acids 828 to 996 (169 residues), 127.5 bits, see alignment E=1.5e-40

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1014 amino acids)

>mRNA_4060 K01537 E3.6.3.8 Ca2+-transporting ATPase (Rhodosporidium toruloides IFO0880)
MPSDLKKTAYSHLLPQHHADSPSSSSPASSRSSSPAPLPADDKHYAFSTTLRRHEPESVV
DFSHPLSDLKQHVAARFTGYEPVGGQGGTAAGQTGPSAYPPAAHGHAGPGGYSHHPFAHT
TSPLTPSAHFASQSIAQTLSALSTSASSGLDAGKVGAIRELSGPNEFEVEAKDPTWKKFL
GKFYEDPLILLLMASAAVSAVVGNYDDAASILVAVFIVVTVGFVQEQRSEKSLEALNRLV
PHYCHLIRNGRKTTQLANVLVPGDLVTFHTGDRIPADIRLTQAHGLEIDESALTGETRPA
KKHTDAITPGTGGMGGLPISERDNIAFMGTLVRSGRGEGVVVGTGVQTEFGVVFSMMQEV
GDKKTPLQVSMDELAKKLSIISFGVIGVICLIGVIQHRSWLEMFTIGVSLAVAAIPEGLP
IVVTVTLALGVLRMSKRNAIVKKLPSVETLGSVSVICSDKTGTLTTNVMTVTKAYSIDHG
IFALDHGPPMLSPDDSRAKIFLVGNLCNHAHADKGKYHGQATEVALMNALATVGLTDQRK
FFTRKSEVAFSSETKTQSVTGTFSHAQPGEPDTTYVSGALEGVLARCRYHLREDNSVVPL
EAGVSKLIHSKAIELASSGLRVVAMAYGQDPEALIFAGLQGMMDPPRPGVADAISKLSSG
GIHVVMITGDSEQTAVAIAKQLGIRTTGGTSRMGILTGKEIDLLSQRQLADRIGGVTVFA
RTTPRHKMAIIEAYQSRGAVVAMTGDGVNDAPALKMADIGVSMGKGGTDVAKEAADVILV
DDNFTTLLPAVEEGKGIFVNIQNFLCFQLSTAVAALSLITLSTALGLPNPLNAMQILFIN
VIMDGPPSQSLGVDPVDREAMKRPPRPKSAPILTRRLMYRVGFSASIIILGVLFVLAREL
GDGTDLARDQTMTFTSFVFLDLASALQNRGLNVPLLTGTPNKMLLLAVSVSFLVQLSLVY
VPFLQSVFQTQALSLRDLSVLLVLGGCSMSIHEWRRRYERKQLVEEAWTNAQVV