Protein Info for mRNA_4196 in Rhodosporidium toruloides IFO0880

Name: 12564
Annotation: K12343 SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 351 transmembrane" amino acids 25 to 45 (21 residues), see Phobius details amino acids 66 to 84 (19 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 143 to 165 (23 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details amino acids 257 to 275 (19 residues), see Phobius details amino acids 303 to 319 (17 residues), see Phobius details PF02544: Steroid_dh" amino acids 141 to 269 (129 residues), 42.1 bits, see alignment E=9.2e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (351 amino acids)

>mRNA_4196 K12343 SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Rhodosporidium toruloides IFO0880)
MASSATSYLTHLVEGLQGQYGTVGLYAAVQRLFVGFGFVGGPGSCVIDAPFGKFGTWKRF
AVHGDIGWMLMEIVSPLAFLYGLSLPLNTSSSSFLSFAPFRIVSAFRALPLARQVLAGAY
LVHYANRSVISSIRNPGRARMNIIIPLLSALFNLANGGTIGVWLAGGIPQTGQAVAKSGL
RDAGWAKPLFFLGAVMWAAGLCSNIYHDEVLYNIKREKQAKEKKGKGKESSSPKDRYSIP
QGGLYRFVSHPSYSSEWFEWLGFLFATFALAPGPVPPTPVSSLIPSLSLKALPSPLKPLK
GWYLQPPALFLWQEIGAMLPRARSGHAWYRKTFGKEWEEKGAKWIVFPGVY