Protein Info for mRNA_4198 in Rhodosporidium toruloides IFO0880
Name: 12566
Annotation: K00166 BCKDHA, bkdA1 2-oxoisovalerate dehydrogenase E1 component alpha subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00166, 2-oxoisovalerate dehydrogenase E1 component, alpha subunit [EC: 1.2.4.4] (inferred from 47% identity to afv:AFLA_128600)Predicted SEED Role
No annotation
MetaCyc Pathways
- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA (2/3 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.2.4.4
Use Curated BLAST to search for 1.2.4.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (444 amino acids)
>mRNA_4198 K00166 BCKDHA, bkdA1 2-oxoisovalerate dehydrogenase E1 component alpha subunit (Rhodosporidium toruloides IFO0880) MLVRQTAFTLARSGTRTLATTAIRFHTPLTETCSSSHFFDAVHKGTIPSFRLLGPDGVLV KDAEEEWVQRAKGEDGEKLKRMLEVMTMLPILDQILYSSQRQGRISFYMTGYGEEGTVVG SAAAWENDDEVFAQYREVGVLIWRDYPLSSLMAQVFSTASDIATKGRQMPVHYGSRDHHF HTISSPLGTQLPQAAGAAYALKRTPGRENSCVVCYAGEGATSEGDFHAGLNMASVLGVRP RSFAISTPVSQQYAGDGIAARGPGYGIETVRVDGNDPLAVYLACKEARRKAVEGQKPVLV EAMTYRVGHHSTSDDSSAYRSLSAVESVKKLDSPIHRLRRYLESLSPALWSAEHDAKIKD ESKRAILREFSKAEKEKKPPLAEMFGDVFAPVEGEDAQQHGGLERPQYEQKAELKRLIEK WGETQTWKKELEKFAGGKEAVTKW