Protein Info for mRNA_4294 in Rhodosporidium toruloides IFO0880

Name: 12662
Annotation: K08851 TP53RK, PRPK, BUD32 TP53 regulating kinase and related kinases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 TIGR03724: Kae1-associated kinase Bud32" amino acids 70 to 291 (222 residues), 138.6 bits, see alignment E=9.1e-45 PF06293: Kdo" amino acids 173 to 246 (74 residues), 34.3 bits, see alignment E=3.2e-12 PF02958: EcKinase" amino acids 189 to 239 (51 residues), 23.1 bits, see alignment 8.6e-09 PF01636: APH" amino acids 192 to 241 (50 residues), 24.6 bits, see alignment 4.7e-09

Best Hits

Predicted SEED Role

"p53-regulating protein kinase (human PRPK/yeast YGR262c)" in subsystem YgjD and YeaZ

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>mRNA_4294 K08851 TP53RK, PRPK, BUD32 TP53 regulating kinase and related kinases (Rhodosporidium toruloides IFO0880)
MPNLHKDVKAAVDATQLGAPVHELISRSHLIKQGAEGKVYKSTLLPSPAMIRSTSAAVSA
DPTPPPPVPILLKYRFPKRYRHPTLDAQLTRQRLTSEARALVRCMKAGVTVPGLRLVDVT
QGCLGMEWIDGWSVREILGGGQDDVAEDAEEEVVADESLGSPEDVLRDAGIDEDAMLRAI
GCEIGKMHLADIIHGDLTTSNMMVRLTNTPQRFELVLIDFGLSSTSPMHEDRAVDLYVLE
RAFSSTHPVQPGGVAHFEVVLEGYREALQRSKKGEWERVEKRLEEVRMRGRKRSMVG