Protein Info for mRNA_4380 in Rhodosporidium toruloides IFO0880

Name: 12748
Annotation: K00550 OPI3 methylene-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 transmembrane" amino acids 14 to 32 (19 residues), see Phobius details amino acids 52 to 72 (21 residues), see Phobius details amino acids 92 to 119 (28 residues), see Phobius details amino acids 141 to 158 (18 residues), see Phobius details amino acids 164 to 190 (27 residues), see Phobius details PF04191: PEMT" amino acids 92 to 192 (101 residues), 104.3 bits, see alignment E=2.4e-34

Best Hits

Swiss-Prot: 59% identical to PLMT_NEUCR: Phosphatidyl-N-methylethanolamine N-methyltransferase (chol-2) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

KEGG orthology group: K00550, methylene-fatty-acyl-phospholipid synthase [EC: 2.1.1.16] (inferred from 62% identity to fgr:FG08613.1)

MetaCyc: 49% identical to phospholipid methyltransferase (Saccharomyces cerevisiae)
Phosphatidyl-N-methylethanolamine N-methyltransferase. [EC: 2.1.1.71]; 2.1.1.71 [EC: 2.1.1.71]

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.16 or 2.1.1.71

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (220 amino acids)

>mRNA_4380 K00550 OPI3 methylene-fatty-acyl-phospholipid synthase (Rhodosporidium toruloides IFO0880)
MAGLLSYVDFSQKSFWVSFASIIFNPLAWNIVARQEYRNKVLTKLAGGNRYAACYGLAVA
IFTAGIFRDHLYKNALGDQPSHPFLHYTEFKILAAILFLTGSTLVVTSTWALGITGTFLG
DYCGILMDHKVESFPFNVTSQPMYLGSTLNFLAIALWYESPAGLLLTLHVYIVYQIALSY
EDPFTVAIYAKREQDRAKGKGKAIEDAEGSSTAVQGHKEL