Protein Info for mRNA_4459 in Rhodosporidium toruloides IFO0880

Name: 12827
Annotation: HMMPfam-PH domain-PF00169,ProSiteProfiles-PH domain profile.-PS50003,SMART-Pleckstrin homology domain.-SM00233,SUPERFAMILY--SSF50729

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 736 PF14593: PH_3" amino acids 146 to 245 (100 residues), 34.1 bits, see alignment E=5.2e-12 PF00169: PH" amino acids 151 to 242 (92 residues), 73.1 bits, see alignment E=4.9e-24 amino acids 523 to 646 (124 residues), 46.5 bits, see alignment E=9.6e-16

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (736 amino acids)

>mRNA_4459 HMMPfam-PH domain-PF00169,ProSiteProfiles-PH domain profile.-PS50003,SMART-Pleckstrin homology domain.-SM00233,SUPERFAMILY--SSF50729 (Rhodosporidium toruloides IFO0880)
MSEPQPIPRQTAPPTPQEIERKLGSPSLPPPGSSVVSVAGSLERQGLERRESGSGAPRRA
HGSMSSGVSSNDEGTDEDGHPSPLHRPTNLPLSAISEAEDAIGSGSDGEESDASSIGGNE
RNPAFAAVGGGEVASRTSRDSAGLSDNVALKAGYLMKRGERRKTWKKRWFVLRGGQVAMY
KNDKEYRLLRLIPLTDIHTVTPVEMKKHAHTFGIVTPRRTFYIKADSDADVNAWCRVIER
AKAEYLARATVTTLDTPNSTEQATPTNGPTPSQTPRQMSFSAIGPPTPDTVQPVSHPQAI
AIPGSSAPSVGGSFTPTSYTTTSSSVGGSNLLGTSYASTTSSLGPAAPPSSGSRAPPNSL
ITPGPMATAVPGGLGLHSPSVGDLELQGLDARLEQMDLAPPPPLGAPRPSPQRSMSGRSD
ILAVPSAAMHGVGRGRSGSSATGGSSSLASGVAGSGMAAMSSSEEEDGFDPGYDYPTFSP
PTAPPVPDPSLVYQQPQVSAQPQQVSSPPAQQPLTTPANRNKVILSGYLMKQGKRKTWRK
RWFVLTSGMLMYSRSHMDNKFNRQIPLNAILDAIEYEPPQPASNAHKRTSVVSASSPNPT
SPSLASPVVEGGKTLAHTFKIITPKRTYLVCAPSEEDEIKWLAALQCLVARRTQAQVGSD
VPPTPSAQAPATSPSSAPVPPAAPKRTPSHPGPPPVAGRPIHGRQRSVTDAAKQAVMDVE
RRFHPAKEGAEQVVGA