Protein Info for mRNA_4478 in Rhodosporidium toruloides IFO0880

Name: 12846
Annotation: K01537 E3.6.3.8 Ca2+-transporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1101 transmembrane" amino acids 74 to 100 (27 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 242 to 260 (19 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 313 to 335 (23 residues), see Phobius details amino acids 341 to 366 (26 residues), see Phobius details amino acids 817 to 838 (22 residues), see Phobius details amino acids 844 to 866 (23 residues), see Phobius details amino acids 906 to 932 (27 residues), see Phobius details amino acids 959 to 978 (20 residues), see Phobius details amino acids 1005 to 1026 (22 residues), see Phobius details amino acids 1039 to 1059 (21 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 29 to 97 (69 residues), 52.7 bits, see alignment 7.1e-18 TIGR01523: potassium/sodium efflux P-type ATPase, fungal-type" amino acids 35 to 1067 (1033 residues), 1186.3 bits, see alignment E=0 PF00122: E1-E2_ATPase" amino acids 137 to 272 (136 residues), 106.1 bits, see alignment E=4.1e-34 TIGR01494: HAD ATPase, P-type, family IC" amino acids 303 to 415 (113 residues), 76 bits, see alignment E=2.2e-25 amino acids 733 to 838 (106 residues), 94.2 bits, see alignment E=6.4e-31 PF00702: Hydrolase" amino acids 394 to 772 (379 residues), 65.9 bits, see alignment E=1.7e-21 PF13246: Cation_ATPase" amino acids 494 to 584 (91 residues), 63.6 bits, see alignment E=3.8e-21 PF00689: Cation_ATPase_C" amino acids 848 to 1060 (213 residues), 76.3 bits, see alignment E=6.4e-25

Best Hits

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1101 amino acids)

>mRNA_4478 K01537 E3.6.3.8 Ca2+-transporting ATPase (Rhodosporidium toruloides IFO0880)
MPSSSPAASDKEKQLSKTLSGATAAETHWFLLPPKDVASRLETSIDDGLTANEATARQKR
DGPNELMGGGGVSIWSILAGQVFNAMVLVLVACLAVSFGIQSWIEGGVIAAVIIINVGVG
FLQEYSSAKTMDSLRSLASPNAHVIRNSKIVTIPSPEVVVGDIIEVKTGDTIPADLRLVE
AVNFETDEALLTGESLPVAKDANASWAEEAKASDFDPRDIGVGDRITMAYSSSTVTKGRA
KGIVVGIGMNTSIGAIAQSLRGGDSKVRKVRRNDDGHAPWHRYPAAWALTTLDIIGQFLG
VNTGTPLQRTLSWLAIALFFIGCLFALFCFAANSFRGNKEIILYAIATALSMIPASLVVV
LTITLAGGTRAMVARHVIVRKLDSLEALGAVTNICSDKTGTLTQGKMVVRAAWLPSRGTI
SVGESNEPFNPTLAQLSFSPSSPAKSADQADKPAASSPSSESAPPPSSAETTTPDALLEK
GGSELTTLLNIASMCSTAKVFKKEGEGWTARGDPTECAIQTFAHRFGWGRERWIEGDSRE
WTQVAEYPFDSDVKRMSVLYARKEKQFAFMKGAVERLIDACSQIQLEDGPAPIDDSIKEQ
IFANVEALAEQGLRVLALAAKPWSGASSSSGNPDRAQIETDMTLYGLVGIYDPPRPETKG
SVRMCHEAGIQVHMLTGDHAATARAIALQVGILPRNVNLMSKDSAKAMVMTAAEFDKLSD
DEVDKLPLLPLVIARCAPHTKVRMIEALHRRKAFCAMTGDGVNDSPSLKRADVGVGIGSG
SDVAKDASDIVLADDNFASILAAVEEGRRMFANIRKFVLHLLAGNVMQALTLLIGLAFKD
ENDFSVFPLAPVEILWIIMITSSLPAMGLGAEKAEVDIVPSPIPPSVANAPPDLLQLKMG
VFAPEIIIDILVYGLVGAGCCLGVFTLIVFHWGNGDLGIDSNNNISGNPGSQLVFEARSA
TFATMVWILLFLAFECMDLRRSLFKMDRTPEHRYTQWMHDVWANQILFWSVVGGFLTPFP
LVYIPVINDVVFKHTSISWQWAPAFVATGIFMIFAEAYKYAKRVFIRRRHAKHPEEDDGM
TGVFSAWKTMDPTTRDGKDVV