Protein Info for mRNA_4597 in Rhodosporidium toruloides IFO0880

Name: 12965
Annotation: K01836 PGM3 phosphoacetylglucosamine mutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 59 to 89 (31 residues), 28 bits, see alignment (E = 1.6e-10)
  • amino acids 120 to 176 (57 residues), 34.6 bits, 1.5e-12
• PF00408: PGM_PMM_IV
  • amino acids 457 to 529 (73 residues), 40.5 bits, E=2.5e-14

Best Hits

Swiss-Prot: 49% identical to AGM2_SCHPO: Phosphoacetylglucosamine mutase 2 (SPAC1296.01c) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K01836, phosphoacetylglucosamine mutase [EC: 5.4.2.3] (inferred from 60% identity to uma:UM04983.1)

Predicted SEED Role

"Phosphoacetylglucosamine mutase (EC 5.4.2.3)" (EC 5.4.2.3)

MetaCyc Pathways

• UDP-N-acetyl-D-glucosamine biosynthesis II (5/6 steps found)
• chitin biosynthesis (7/9 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis II (5/7 steps found)
• chitin derivatives degradation (1/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.3

Protein Sequence (547 amino acids)

>mRNA_4597 K01836 PGM3 phosphoacetylglucosamine mutase (Rhodosporidium toruloides IFO0880)
MSLNENAVRTASQAHPRPADITYTYGTAGFRADAEVLDSVMFRVGLLAALRSKKLGGKTI
GVMVTASHNPEKDNGVKLVDPMGEMLHSSWEAYATLLANALSDDALIARLKEVVQTAEID
LSKPAKVVYGYDTRPSCRTLVRAVVDGLSAFDVEQVNAGLVTTPQLHYLTRCLNTEGTPD
AYGEPTIEGYYKKLANAYTTLAKGRHLLPALTVDCANGVGAPKLKEFVKVIGQDILPVIP
VRDHINLAGQLNLNCGADYVKTQQRAPKNVDLVPWQRYCSFDGDADRIVFYYADGEGTFH
LLDGDKIAGLAAGFIMDLVKDAGLGVKVGVVQTAYANGASTKYLTEVLGVPVTCVPTGVK
HLHHAAESYDIGAYFEANGHGTVLFSPSTLTAIRTHTPSTPSQAAALDNLRALVELINQT
VGDALSDMLLVETVLLHRQWTPAQWDAAYSDFPNRLVKVLVQDRHAFTTTDAERKVEKPE
GLQAKIDEAVKDVVGGRSFVRPSGTEDCVRVYAEAATRETADELANKVAYIVFDSYGKGQ
RPVNGFF