Protein Info for mRNA_4627 in Rhodosporidium toruloides IFO0880

Name: 12995
Annotation: K16196 EIF2AK4 eukaryotic translation initiation factor 2-alpha kinase 4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1654 PF05773: RWD" amino acids 6 to 115 (110 residues), 58.7 bits, see alignment 1.4e-19 PF07714: Pkinase_Tyr" amino acids 331 to 468 (138 residues), 26.5 bits, see alignment E=7.6e-10 amino acids 791 to 988 (198 residues), 64.1 bits, see alignment E=2.7e-21 PF00069: Pkinase" amino acids 332 to 473 (142 residues), 42 bits, see alignment E=1.5e-14 amino acids 590 to 659 (70 residues), 46.4 bits, see alignment (E = 7.3e-16) amino acids 791 to 991 (201 residues), 121 bits, see alignment E=1.2e-38 PF12745: HGTP_anticodon2" amino acids 1390 to 1648 (259 residues), 146 bits, see alignment E=3.1e-46

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1654 amino acids)

>mRNA_4627 K16196 EIF2AK4 eukaryotic translation initiation factor 2-alpha kinase 4 (Rhodosporidium toruloides IFO0880)
MEDLKEVQEREIEVLQAIYQEDFAQAESRTAWKAVNAAHEFRVCVRPVEEDLKDKVYVWI
RFKLPQRYPKVAPTMTLEDAKGLASQHLAHLLTTLQRFASSRLGDEMIYDICSQAASYIT
ERHVDSVRGAQPSLEDQRRKRGEEQAKATQEAETRARALKEQQEAEEAARLSQLISEDVR
RKEEVRLERERRERELDRERESGSLEVDARGEKRMKMEVTKGGAKVEAVVKFGYPHSTDW
LGGLFSAQLEISGKTEAVGVFAFDILAPYYLSSQGKRKVAKLEADLDRIFHLSHPRLLST
VGYRIVRYSPGFFPLNPALLPSIRSGEGWTLLVVTPPNRSQSLDELLSTVGELRPDRALA
YFAQLVSAVESLHSYHVVHRAIRPKTIFVTSEKSRSDSSEAAGVKLAGAGWYRRLLDLNR
AEPWLQQPAEEELPDGWVCPEAVSAPFTYDRSRDMYELGVVLAQMLYGLDVTRKFPTPAD
LVRSMPRSSPSIIKRMLNDLLLAEGKKRPTAARLAAQLAEDSGSSTSHGTLVLSATPPKP
LNGWQQLANGQQVLTPLMSPPAAHSARDMAAPSGFFWQPRAAQSRYREEFEELEFLGRGG
GGQVVKARNRLDGHLYAVKKIRLPNDRASEAKILREVTIWSRMNHPNIVRYHTSWTSFDD
PVPSFDALGSGTTLDSNTGTQTLSTTDASTQPSTENDDSGSDDSDSVVDFDEDSTPGDFD
MDFGDELEDNLDFLSVGHAQSQSVSYPSIHFGNEDDPSRPGSERGSPGLSRAGFSKPPTK
ASTPVSTTPKQSRTLYIQMEYVEKLTLREAIEDGISEADSWRWIYQILSAMLHFTSLNII
HRDLKPSNIFIDVKGDVRIGDFGLAVGSSETADVFLAQDGNMDESDLTSGVGTSLYIAPE
TINRGRQGRATKHYNNKVDMYSLGIVFFEMWHPFKTGMERIQVLHDLRRPEIIFPPTWDK
VRLARHTKIVQACLTHDPELRPSPKDLLQSDLLPPRVGDDSIEETIRLLSQPGTTHAQTL
ITALFNQSDEDRLRKDFSYDFYDGSGAKADNDPYAQLVHDKLSRIFRQKGAVQMDSPLLM
PHSQVYASRKPVRLLDADGTIVCLPFQLNIPFCRMVARDTSLTRMKRWTIAPVFRPTQAG
GQPRAVLNAAFDIVSDAVMPAMEAECLFVIEEILSAFPLTGTPAHIINHSKILDALLDIV
PAKQRDAVCDILVQHGRLQRTWVKTASELLKLPGVTRAMCEALGTVDVAGDVGKMRSLVI
SAARRLKHVAQEGFDELKDIVALCRQIGIKNIKVAPLLAANYDLHRDGTIFESHVLRGKT
RDVIAAGGRFDEVVTRLAAPEVRFSGRCPHVVGFSMAIAKLSVAAAEANATVGKQAMTRK
EEHLRSYGPWAIRRCDVYVVSFSPGLIDLRLEIVKDLWRNGIKADLMYDDDFLSLTPEQL
VNACRREGILWLVIVKPSAAGRTVSDESEKSLKVKSVLRGSEDEVGRAELSSWLVKELRE
QSTADEAAGGGAADAAVETSGSSLAEPPKPQQDYIPVLPDDDLRQKGRHNKRTMIVSRAQ
KNVEEAVEAAAHAPVFAVDVDGLSFERMAHSPVWVTNDEAFKTLVQTAPPGKRDYYTSIR
KSIQRTRQKQHISRFWLFSLRDSRSVLMSFFDGV