Protein Info for mRNA_4738 in Rhodosporidium toruloides IFO0880

Name: 13106
Annotation: K01738 cysK cysteine synthase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00291: PALP
  • amino acids 85 to 212 (128 residues), 103.5 bits, E=7.7e-34
  • amino acids 283 to 462 (180 residues), 94.3 bits, E=4.7e-31

Predicted SEED Role

"Cysteine synthase (EC 2.5.1.47)" in subsystem Cysteine Biosynthesis or Methionine Biosynthesis (EC 2.5.1.47)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (7/9 steps found)
• L-cysteine biosynthesis I (1/2 steps found)
• seleno-amino acid biosynthesis (plants) (2/5 steps found)
• superpathway of seleno-compound metabolism (5/19 steps found)

KEGG Metabolic Maps

• Cysteine metabolism
• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.47

Use Curated BLAST to search for 2.5.1.47

Protein Sequence (546 amino acids)

>mRNA_4738 K01738 cysK cysteine synthase A (Rhodosporidium toruloides IFO0880)
MTTTSLIPWALRHPLLALPLPWWIRPTRLGPKRSLVLGLTLGFSLSLSLTGLALYALDAW
KRSLRRKAEKRAIEIRGDEVVDGIEELIGNTPLVRIRSLSDALGVDILGKCEYMNPFGSV
KDRVSLQIIKQAEEEGLIHPDTGSCIFEGTSGSTGISIAGIARARGYKAHIVLPDDVAKE
KIQMLEVFGAEVEPVRPVSIVDRRHYVNLARQRAIEFGKQTVVSTTSGDTPSQTPRSVTP
APSSSSCRNAPDMLVTSRTPPHPSTPSTDAATLQPFTPYRDPPRGVFADQFENTSNMLAH
EQGTAVEIWKQTAGRVDGFVSGAGTGGTIAGVGKVLKEKTGGACEIVLADPQGSGLYHKI
HDGVMYAETESEGKRRRHQVDTIVEGIGLNRITKNLARALPIIDDAFRVTDAEAVAMSRH
LALHDGLFLGSSSAVNLVACVRLARKWGRRGRGKRIVTILCDSGARHTSRFWNDDYLAAA
GIPLPTSIDFLFTEPDSDSLADEAGEAGPDPTHDSELASDDPRELPPPPVELLVPREGVE
RVFGQS