Protein Info for mRNA_4919 in Rhodosporidium toruloides IFO0880

Name: 13287
Annotation: K01768 E4.6.1.1 adenylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2009 PF00788: RA" amino acids 509 to 576 (68 residues), 29.7 bits, see alignment (E = 3e-10) PF13306: LRR_5" amino acids 642 to 751 (110 residues), 16.7 bits, see alignment 2.1e-06 PF13855: LRR_8" amino acids 649 to 706 (58 residues), 31.7 bits, see alignment (E = 3.7e-11) amino acids 695 to 753 (59 residues), 36.6 bits, see alignment (E = 1.1e-12) amino acids 875 to 933 (59 residues), 31.8 bits, see alignment (E = 3.5e-11) amino acids 1057 to 1116 (60 residues), 48.6 bits, see alignment (E = 2e-16) PF13516: LRR_6" amino acids 693 to 706 (14 residues), 10.8 bits, see alignment (E = 0.00016) PF12799: LRR_4" amino acids 1080 to 1119 (40 residues), 29.5 bits, see alignment (E = 2.7e-10) PF00481: PP2C" amino acids 1289 to 1501 (213 residues), 144.2 bits, see alignment E=2.2e-45 PF00211: Guanylate_cyc" amino acids 1568 to 1728 (161 residues), 92.6 bits, see alignment E=8.6e-30

Best Hits

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2009 amino acids)

>mRNA_4919 K01768 E4.6.1.1 adenylate cyclase (Rhodosporidium toruloides IFO0880)
MADYSQAPLVPRSSKQAKMLGVGADIDQRPPGSAGSNLSDWNGWGVQDQAARGRQGSPAD
VAPPWGNGAEPKRKGTLLPSSSSQPLRGTRSASVLRGHAEKEPPVKEKKRGLFGGLLKRR
GSKSDVRDQHSDSGSVSDFGLPPPAQFDSSTLPAKLQARGDAYDLSSSLPSRNGKSSKKS
RRPTTPIGAFVTGSSRNTPTPRQQAVFTNDPEIALDTNLDSMEGIISSAPSTSAGVRPTS
SHERGFGGSVSSGTSGNGLTRSGSGSHASYASNGRRPSLAPSYSDAGPRGAHHGQASAVA
FWNYGGGATAAEQKSAAKAATLMGTAPPAVPGVPGGAPVRPGLGSRTSSQLSLTGGSATP
TQAGMSSSGSTAKGLPPVPRGSAAARTAAVVGGAAGSAGAWTAPDSWAVKAEAGASLDHD
SSEDDVDEDEMEVMDETEESEPGASPRIGTAQTVREGMPDGLAAVKLFGSMETEVLKNGR
PATGGSRPLMRSGRPGTADGEARKASQKPFMVRIYRVDNTFSTLPVPLGATASEMTAMLA
RKFQVNAKTTYALYLREKGLERRVGPNEKPVLLQRRKFEQAGYTELDKLEELGREDNSYL
SKLVYKAQYSTMQGVAEESFAGESMEFVDLSGKGVETIPIFLYKHSHEIRSLNLSRNRPF
DLPTDFIQGCTALRELVLSNMGIKRLPQAIKECQHLTRLDISNNNIVDLEHIALDTLGNL
SSIKCHNNRLSTVPEYFRNFRQLKYLNLSNNRFDKIPLVVCEIEPLLELDFSFNTVTVVP
PEIGQLENLERLNLLANILTSLPSTLGSLISLKELDIRRNVISDFSPLTSIPVLEVLRCE
HNQASTLDASWANIRILTAKHNSLTRFALTGTSTTLTSLNLSYGKLSTLSPEIFGHLGSV
ETLILDNNTLRILPDGIGSLPNLVTFSIKNNLLTSLPDSIGRLQRLQSLQVSGNDLQTLP
SALWLCSQLSTLNASSNLIKDFPDPPLPTVAPAATPTSSLGDGGDELDLRQLAAAVKPPT
TSSGRLAPPLSMSLQRLFLGDNQLGDDVFAPISLMAELRVLNLSFNDIYEIPTSSLFKCQ
SLEELYLSGNKLTSLPPDDLERLVNLKLLYLNGNKLQTLPAELGKIKKLFALDVGSNVLK
YNIANWPYDWNWNWNLELRYLNLSGNKRLEIKPGHQNDTSNLPRSAKRRNLADFSALTKL
HVLGLMDVTLMIPSVPDENEDRRVRTSLSEINDMGYGIADTLGSRFDTLSLVDIVIPRFR
SKDDEAIFGLFDAVNKGQNTGARLVKYLQDAFSAVLTLELSRLKSGEVTSDALRRAFLNI
NRDYGNLLLPALESRRKGSEISLTDKTMSSVRTGAAGIIVYIRRKRLYVANAGNALAVIA
GRGGTARLIAKRHEPFDSGEIARIRTAEGWISHRGYVNDEVDIARSFGFYNVFPAINAAP
DVDEIELTETDEFVIIANRGLWEHMSYQTAVDVARTERSDPMAAAAKLRDLAISYGSSSN
VMVMVLAVGDLFKAKKSGYYAKHRAAHGEDEGFYGAHKAGVVAGRRGKGEEGAGERYLNL
LDREVPPPVGMVALVFTDIRNSTALWESNPGMQTAIRMHNQLLRRQLRAIGGYEVKTEGD
AFMVSFPTVTSALLWCLTVQLELLREDWPQEILDSEEGKEILDSRGEILYRGLSVRMGIH
WGAPVCEADPITRRMDYFGPIVNRAARISAVAEGGQISASQDVIDIIQDVVMQQKPGPSS
LDSDDGEEEEDPEEYLDPRDKQDIAALRRLGFGITELGERKLKGLESAELISLIWPRVLK
ERIVPASADQDGSAAAAEIAKKTEVVQDETPQLLDVNTIKALGKVVQRLESVCGALVHGV
ENGLATPPHVPNSSARPSTPAQQAVAAKRKTLIHPTSFAFPVRADATDDELCALLESYLV
RIENCLSTLTLHQLGPFTEVLSALGQALRVDQRSVLLALTRFAGLQQQQAMLLQAQASKP
PSPAPDRPLSSGTVSRAGQPPAAPSFRQA