Protein Info for mRNA_5334 in Rhodosporidium toruloides IFO0880
Name: 13702
Annotation: K14563 NOP1, FBL rRNA 2'-O-methyltransferase fibrillarin
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 72% identical to FBRL_DEBHA: rRNA 2'-O-methyltransferase fibrillarin (NOP1) from Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
KEGG orthology group: K14563, rRNA 2'-O-methyltransferase fibrillarin [EC: 2.1.1.-] (inferred from 77% identity to mgl:MGL_3697)Predicted SEED Role
"Fibrillarin" in subsystem Ribosome biogenesis archaeal
KEGG Metabolic Maps
- Alkaloid biosynthesis I
- Anthocyanin biosynthesis
- Benzoxazinone biosynthesis
- Biosynthesis of alkaloids derived from shikimate pathway
- Carotenoid biosynthesis - General
- Flavonoid biosynthesis
- Histidine metabolism
- Insect hormone biosynthesis
- Naphthalene and anthracene degradation
- Phenylpropanoid biosynthesis
- Porphyrin and chlorophyll metabolism
- Tryptophan metabolism
- Tyrosine metabolism
- Ubiquinone and menaquinone biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 2.1.1.-
Use Curated BLAST to search for 2.1.1.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (309 amino acids)
>mRNA_5334 K14563 NOP1, FBL rRNA 2'-O-methyltransferase fibrillarin (Rhodosporidium toruloides IFO0880) MAFSGGRGGGFSARGGAGGGRGGARGGGRGGGRGGAPRGGGRGGAGGRGGRGGARGGKGG VGAKGGAKVILEPHRHPGVFVAKGKEHLLVTRNLVPGESVYGEKRISIEQPNADPNLPAE KVEYRVWNPFRSKLAAGILGGLDDIHIGPGKKVLYLGAASGTSVSHVADVVGPEGTVYAV EFSHRSGRDLVNMAKKRTNVIPIVEDARHPNKYRMLLSMVDVVFADVAQPDQARIVALNA HHFLKRGGHAVISIKASCIDSTAPAEAVFAAEVKKLQSEGFKPREQLTLEPYERDHAMLV ATYSRDAAK