Protein Info for mRNA_5392 in Rhodosporidium toruloides IFO0880

Name: 13760
Annotation: KOG0166 Karyopherin (importin) alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 PF01749: IBB" amino acids 8 to 92 (85 residues), 95.6 bits, see alignment E=8.9e-31 PF00514: Arm" amino acids 103 to 142 (40 residues), 42.8 bits, see alignment 1.7e-14 amino acids 145 to 183 (39 residues), 48.1 bits, see alignment 3.6e-16 amino acids 186 to 227 (42 residues), 39.4 bits, see alignment 2e-13 amino acids 239 to 269 (31 residues), 26.3 bits, see alignment (E = 2.7e-09) amino acids 271 to 310 (40 residues), 33.5 bits, see alignment 1.4e-11 amino acids 314 to 353 (40 residues), 44 bits, see alignment 6.9e-15 amino acids 355 to 394 (40 residues), 45.9 bits, see alignment 1.8e-15 amino acids 402 to 438 (37 residues), 31.3 bits, see alignment 7.2e-11 PF13646: HEAT_2" amino acids 118 to 222 (105 residues), 29.1 bits, see alignment E=4.7e-10 PF13513: HEAT_EZ" amino acids 129 to 182 (54 residues), 35.7 bits, see alignment 4.4e-12 PF02985: HEAT" amino acids 157 to 183 (27 residues), 22.9 bits, see alignment (E = 3.2e-08) PF16186: Arm_3" amino acids 453 to 498 (46 residues), 70 bits, see alignment 4.5e-23

Best Hits

Swiss-Prot: 72% identical to KAPA_EMENI: Importin subunit alpha (kapA) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

KEGG orthology group: None (inferred from 78% identity to cnb:CNBD1560)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (530 amino acids)

>mRNA_5392 KOG0166 Karyopherin (importin) alpha (Rhodosporidium toruloides IFO0880)
MERQAASRRAQYKNKGIFGQDELRRRREEAQVEIRKQKREETIAKRRNLNAASSGADSDD
ESGVDSSFLDQLPAMIQGVFSDQPDQQLDATTKFRKLLSKERNPPIEKVIECGVVARFVE
FLRSSHSMIQFEAAWALTNIASGTSEHTQVVIESGAVPVFIELLSSPVLDVREQAVWALG
NIAGDSPKCRDYVLEQGALRPLLALLNEPHKMSMLRNATWTLSNFCRGKNPQPNWELISP
ALPVLTKLIYSLDDEVLIDACWAISYLSDGSSDKIQAVIESGVVRRLVDLLMHHSTAVQT
PALRSVGNIVTGDDLQTQVVLATGALPALLALLSSPKEGIRKEACWTISNITAGSPAQIQ
SVIDANIVPPLINVLQHADFKTKKEACWAISNATSGGLQEPSQIRYLVSQGCIKPLCDLL
TSTDNKIIQVALDGLENILKVGEADKEQNGGVNQYALFVEEAGGMVAIHNLQHHENLEIY
KKAFDMMDRYFPDDEGDETGLGDAQVDEQGAFALSNVQAPQGGFSFGNMS