Protein Info for mRNA_5416 in Rhodosporidium toruloides IFO0880

Name: 13784
Annotation: K04496 CTBP C-terminal binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00389: 2-Hacid_dh
  • amino acids 75 to 336 (262 residues), 26.3 bits, E=7.6e-10
• PF02826: 2-Hacid_dh_C
  • amino acids 134 to 314 (181 residues), 156.4 bits, E=7.6e-50
• PF03446: NAD_binding_2
  • amino acids 175 to 280 (106 residues), 28.7 bits, E=2.2e-10

Best Hits

KEGG orthology group: None (inferred from 39% identity to ang:ANI_1_650034)

Predicted SEED Role

"D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)" in subsystem Glycine and Serine Utilization or Pyridoxin (Vitamin B6) Biosynthesis or Serine Biosynthesis (EC 1.1.1.95)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (7/9 steps found)
• superpathway of L-serine and glycine biosynthesis I (3/4 steps found)
• L-cysteine biosynthesis IX (Trichomonas vaginalis) (2/3 steps found)
• L-serine biosynthesis I (2/3 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.95

Use Curated BLAST to search for 1.1.1.95

Protein Sequence (356 amino acids)

>mRNA_5416 K04496 CTBP C-terminal binding protein (Rhodosporidium toruloides IFO0880)
MPVPIPTPTSAHPRILMLGDPPYLRLEQWKHFQQRFEVVSADLPSREGFMQALREKRYGD
FEGIVKFAVETGNGASPWNEELISLLPSSVRLFAAAGAGFDYLSLPALNARNIAFANSRG
AGDTATSDIALFLILATFRLTSYSEWAARTGDPKVFHEVHLEIGKKARNPSGKTLGCVGL
GAIQREVARKARALGMRVCYYDVVPPPEEVVKALEAERCETLQELAGKADCVSVSVPYMD
STHHLIDAPFFAAMKPNSRIVNTARGPVIDQAALIEALKSGHLLSAGLDVHEFEPQVSRE
LIEMKQVTLTTHIGGVAQETFVEFERLVMSNTERFLLDGEQLLTPIGKQFEPSKAQ