Protein Info for mRNA_5608 in Rhodosporidium toruloides IFO0880

Name: 13976
Annotation: K03018 RPC1, POLR3A DNA-directed RNA polymerase III subunit RPC1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1804 PF04997: RNA_pol_Rpb1_1" amino acids 361 to 707 (347 residues), 282.8 bits, see alignment E=9.5e-88 PF00623: RNA_pol_Rpb1_2" amino acids 709 to 876 (168 residues), 241.9 bits, see alignment E=1.1e-75 PF04983: RNA_pol_Rpb1_3" amino acids 880 to 1060 (181 residues), 136.1 bits, see alignment E=2.6e-43 PF05000: RNA_pol_Rpb1_4" amino acids 1085 to 1191 (107 residues), 101.3 bits, see alignment 7.6e-33 PF04998: RNA_pol_Rpb1_5" amino acids 1198 to 1727 (530 residues), 266.5 bits, see alignment E=7e-83

Best Hits

Predicted SEED Role

"DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6)" in subsystem RNA polymerase III (EC 2.7.7.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.6

Use Curated BLAST to search for 2.7.7.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1804 amino acids)

>mRNA_5608 K03018 RPC1, POLR3A DNA-directed RNA polymerase III subunit RPC1 (Rhodosporidium toruloides IFO0880)
MSMLADAGRLLQRNLGHLRPPPIAGKKHNKVPTYFRPRPKFVKLKDRIPFWYIAPGDKVQ
LIKGDRELKNVTGVVDKVDRMTNRVMLKGTEFAHKKRQPAEYKGQALDPNYNPPDGGVYY
VPRSFHVSNLRLVYTHKNQEYLATRIRKSKVTWNRRLRRFSWRRYVLVPALATNHGAAQW
RRLVWPVEDRPKYGGNKNPAVVCEQQEAMRNNFMPDLSKLSLVPRPEEISRDPSKYPKLP
TDAPPEVKVGILDVGGAYWSRANRMKRMLSLRLPVSFALRLSQHPLALVHATCWPAPIAE
PLKYRQVARQAPSADLTSGRRGQVERAFAALLKGSMTLYRPRAAFERDADSTLSPSSTHS
KHIQFSVLSSREAVAISEFEANQRDLYTPGDRRPVEHGVLDKRLGTSDKTGKCDTCGLGL
ADCVGHYAYIKLVLPVFHIGYFKHILSILQCICKTCSRILLDSSQHRKYLALFRRPNLDS
LTIAAYSKQLAALCRKCTTCPHCGAINGVVKKIGTMRIGHEKWRGRNLKKDAGGRDGAEG
KGNYTAWRESFAEAVKEDKMLEPHIDKAIDDLNPLKVLTLFRKITSSDCELLGLDPTAGR
PEEFLWQYISVPPVCIRPSVAQEAATNEDDLTVKLTEIVFMNAVIKTGLAKGVTTQNLME
QWDFLQLAVATYINSEMPGIPTAMGQKPMRGLCQRLKGKQGRFRGNLSGKRVDFSGRTVI
SPDPNLMIDQVAVPERVAKILTYPERVTAHNIERLRQAVRNGTDVHPGANFINQGGGDGS
KKFLKYGDREFMADKLRVGDVVERHLRDDDIVLFNRQPSLHRLSILSHRVKVRPWRTFRL
NECVCTPYNADFDGDEMNLHVPQTEEARTEAFQLMNIKRNLVTPRNGEPIIAATQDFITG
CYLITRRDTFFNRQEFVQMCSYLQDAELEIELPPPTILKPERLWTGKQVFNVLMRPNKDS
PVNVNLECKNKTFGKPSTEFDMSYPNFMSVNDGYLVVQNSEIISGVFDKSTVGDGNKKSV
FAVIQRDFGEDHAAKCMNRMAKLCARWLANKGFSIGISDVTPGERLKAEKDDLVRRAYGQ
ADEYIEKAARGKLECQPGSNLEQTLESLISGDLSRVRDQVGEICMTELSRNNAPLIMATC
GSKGSKINVSQMVACVGQQIIAGHRVPNGFQDRSLPHFPKGAIDPLAKGFVSNSFYSGLR
ATEFLFHAISGREGLVDTAVKTAETGYMARRLMKALEDLSSRYDRSVRNATGGVVQFIYG
DDGLDPANLEGDGKPVVFERTWAHARVSSPSSPPPAVHEFDGFFAQALRLDVNEEGLLPY
EINRLVAEKTATPYFTNSCSEEFLRELREFVDQQIAQQAAKYREEYGMPPALAPLKRNQS
KFGKADAAMQAIVNNKTKVTVTQIEEFLQLCWTKFVKAKIEPGSAVGAIGAQSIGEPGTQ
MTLKTFHFAGVASMNVTLGVPRIKEIINAAKTISTPIISAKLFQDKLEQAARIVKGRVEK
TYLGDVSHRLITLVSLELTDLVVQIASVIAGVYSQGQMYVSVHIDMRAIRALQLEVTLDS
IAASISSAPRLKIKSADITVKRHTDEIHIVAHHNGEDKMPAYRRLMWLRRVLPSISVKGV
PGLQRAVIQQNGEGIKELLVEGEGLREVMVTDGVIGTQTKSNHVMEVEKVLGIEAARKTI
IDQIHYTMDSHGLGVDPRHLMLLGDVMCFKGEVLGITRFGVSKMKDSVLMLASFEKTTDH
LFDASFNARRDPIQGVSECIILGSPANNVGTAMPALVADKPKLPPRYQTLFERPEKVKKG
KARA