Protein Info for mRNA_5622 in Rhodosporidium toruloides IFO0880

Name: 13990
Annotation: K00849 galK galactokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF10509: GalKase_gal_bdg" amino acids 68 to 116 (49 residues), 74.7 bits, see alignment 5e-25 PF00288: GHMP_kinases_N" amino acids 203 to 273 (71 residues), 49.6 bits, see alignment E=5.9e-17 PF08544: GHMP_kinases_C" amino acids 544 to 617 (74 residues), 54.1 bits, see alignment E=2.6e-18

Best Hits

Predicted SEED Role

"Galactokinase (EC 2.7.1.6)" in subsystem Lactose and Galactose Uptake and Utilization (EC 2.7.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (648 amino acids)

>mRNA_5622 K00849 galK galactokinase (Rhodosporidium toruloides IFO0880)
MTLSSSPRRPARSSLVFFSSYPLDSLAVRCETMPSLETSPLPLADSLDQVYTQAALSHEG
ERWNEVFEEFKREYGVAVDKVARAPGRVNIIGEHIDYCGFSVLPAAIERDVLVAFSTASP
SSSSKDIPSPSEKGKTVFVLRNSSSKFSPTSFEVDLTGDGTDLALPQEHHWSSYFIAGTK
GILGHLYRKPRQSDFTPPERVLVLVNGTVPEGSGLSSSSAMTTASAISVLEIVGRREGDD
GISRRDVTNVAIESERLVGVNSGGMDQSASVFSRPMHLLHIEFIPTLEARAIPLPQTNPP
FSFVIANTLVTSNKKVTAKYHYNLRVVECRLGALLLAKFLGLHYTHETRPFPSYKTLLDA
YFKNRGPTHGPIRSNSQRPEKLVPDGATVPALPSSRLPPKTASGTHELKTMLGLIGQALG
GPGMEDGMTWEQVAERLEVDPKVLEKSVTDREVEPKDGRFKLWTRARHVFTEALRVYEFK
DLLCDTAATSQRASPSDIEDGHTTPILETSASDSLPDLQTAPVDPYSTSSLAVPKHADPS
SYLLEQMGKLMNESMESCQKDYECSCPELDELVSIARENGALGSRVTGAGWGGATVSLVR
EPDVPRFIDALKSDYYNKRFPKLSEQELSDAVLATKPEHGALLFQNSD