Protein Info for mRNA_5792 in Rhodosporidium toruloides IFO0880

Name: 14160
Annotation: K10755 RFC2_4 replication factor C subunit 2/4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00004: AAA
  • amino acids 148 to 262 (115 residues), 40.6 bits, E=5e-14
• PF13177: DNA_pol3_delta2
  • amino acids 184 to 266 (83 residues), 40.6 bits, E=3.5e-14
• PF08542: Rep_fac_C
  • amino acids 331 to 417 (87 residues), 82.2 bits, E=4.6e-27

Predicted SEED Role

"Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1)" in subsystem Arginine Biosynthesis extended (EC 2.3.1.1, EC 2.3.1.35)

MetaCyc Pathways

• L-arginine biosynthesis II (acetyl cycle) (9/9 steps found)
• L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (7/9 steps found)
• L-ornithine biosynthesis I (4/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.1, 2.3.1.35

Use Curated BLAST to search for 2.3.1.1 or 2.3.1.35

Protein Sequence (438 amino acids)

>mRNA_5792 K10755 RFC2_4 replication factor C subunit 2/4 (Rhodosporidium toruloides IFO0880)
MEMEERGEQDRESDWRDCERAQLQFPSTSTADKGKQPQQDEPVQYELPWCALTLPRLGRE
GVFAKGRLLLRSTAPLTRSSLLPRPSLPTSPPLYPSTTPFLRAQHRPKTLDDIVGNTETI
ERLKVIARDGNCPHIIISLVERWVRTQGAPGIGKTTSILALARALLGDKNYKEGVLELNA
SDERGIDVVRNRIKTFAQKKVTLPLGRHKLIILDEADSMTTGAQQALRRTMELYSNTTRF
ALACNQSNKIIEPIQSRCAILRYARLSDKELLKRLKEICEIEKVPHNEQGLTALIFTSEG
DMRQAINNLQSTFSGFGFVGADEVFKVCDQPHPVRVQQLVSACVKGDVDKAMDGLGELWG
QGYAAVDVVSTLFRVVKGMEQLSEYVRLEFIREIGFTHMRILEGVATVVQLGGLIARLCR
LSMKPELFKLPGKDGVQL