Protein Info for mRNA_5899 in Rhodosporidium toruloides IFO0880

Name: 14267
Annotation: K00038 E1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00106: adh_short
  • amino acids 10 to 205 (196 residues), 165.7 bits, E=1.4e-52
• PF08659: KR
  • amino acids 13 to 182 (170 residues), 34.7 bits, E=2.7e-12
• PF13561: adh_short_C2
  • amino acids 16 to 253 (238 residues), 186.2 bits, E=1.1e-58

Predicted SEED Role

"3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 1.1.1.100)

MetaCyc Pathways

• biotin biosynthesis I (11/15 steps found)
• gondoate biosynthesis (anaerobic) (3/4 steps found)
• palmitate biosynthesis II (type II fatty acid synthase) (22/31 steps found)
• (5Z)-dodecenoate biosynthesis II (4/6 steps found)
• stearate biosynthesis II (bacteria and plants) (4/6 steps found)
• palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) (6/9 steps found)
• 8-amino-7-oxononanoate biosynthesis IV (3/5 steps found)
• fatty acid elongation -- saturated (3/5 steps found)
• 8-amino-7-oxononanoate biosynthesis I (7/11 steps found)
• oleate biosynthesis IV (anaerobic) (9/14 steps found)
• (5Z)-dodecenoate biosynthesis I (3/6 steps found)
• stearate biosynthesis IV (3/6 steps found)
• cis-vaccenate biosynthesis (2/5 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (9/16 steps found)
• octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) (6/12 steps found)
• superpathway of fatty acid biosynthesis II (plant) (28/43 steps found)
• petroselinate biosynthesis (1/6 steps found)
• superpathway of unsaturated fatty acids biosynthesis (E. coli) (11/20 steps found)
• superpathway of fatty acids biosynthesis (E. coli) (34/53 steps found)
• palmitate biosynthesis III (14/29 steps found)
• tetradecanoate biosynthesis (mitochondria) (11/25 steps found)
• streptorubin B biosynthesis (14/34 steps found)
• anteiso-branched-chain fatty acid biosynthesis (13/34 steps found)
• even iso-branched-chain fatty acid biosynthesis (13/34 steps found)
• odd iso-branched-chain fatty acid biosynthesis (13/34 steps found)
• mycolate biosynthesis (20/205 steps found)
• superpathway of mycolate biosynthesis (21/239 steps found)

KEGG Metabolic Maps

• Biosynthesis of unsaturated fatty acids
• Fatty acid biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.100

Use Curated BLAST to search for 1.1.1.100

Protein Sequence (256 amino acids)

>mRNA_5899 K00038 E1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase (Rhodosporidium toruloides IFO0880)
MAAANSLEGKVAIVTGGASGIGFASVKAFLAAGALGVTIVDLTSSALSHAVSLLSPSDHS
RILTYTGDVSHPSTAAEYVAKTVEKWGRVDVSVQCAGISLPSKNVVDMDVEEFDKTISVN
LRGVFLGLQQSLKAMLASPSGGKGCSVVLVSSQLAFDGYPGSAPYSASKAALRGLMTSVA
QEVGPQGIRVNAVAPGPIDTPMLADFPSEGHTTKGNIKRAGQPEEVANAILYLSSEMGSY
CSGTTLKCDGGWSKWC