Protein Info for mRNA_5972 in Rhodosporidium toruloides IFO0880

Name: 14340
Annotation: K03243 EIF5B translation initiation factor 5B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1227 PF00009: GTP_EFTU" amino acids 630 to 839 (210 residues), 111.2 bits, see alignment E=1.3e-35 TIGR00231: small GTP-binding protein domain" amino acids 631 to 757 (127 residues), 66 bits, see alignment E=1.8e-22 PF01926: MMR_HSR1" amino acids 631 to 754 (124 residues), 26.2 bits, see alignment E=1.8e-09 PF03144: GTP_EFTU_D2" amino acids 867 to 943 (77 residues), 35.4 bits, see alignment 2.9e-12 PF11987: IF-2" amino acids 976 to 1068 (93 residues), 72.9 bits, see alignment 5.3e-24

Best Hits

KEGG orthology group: K03243, translation initiation factor 5B (inferred from 62% identity to ppl:POSPLDRAFT_134953)

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1227 amino acids)

>mRNA_5972 K03243 EIF5B translation initiation factor 5B (Rhodosporidium toruloides IFO0880)
MPPKNKKGSKKPLRDDDEYWESLANKSGKASPAATGSPAAGQGGASPSASDSEDEGRLVK
RGGKKGKGGGGGFASFADMMVDEGEDDADEAAPTKVEEEEEEDGLLAMAKKAASSKKGGK
KDKRKKNAVTDDDYVFDEPSPAAAEEPKEEEVDLAAPRGAVEVNDDWMEEEFGPSKGKKG
KGGKKGGKKQHQAVEEDEAVEEVTKKVEDVKIEEKKEESAPAAAVADEDEEEGGEVKKVL
SKKEKEKLKKEKEKAKKKAQAAAKKASEPAATSPSTETPSAPAAAPTDDAAADEGGDEPS
SSKNKKKKKKKGGAAEPVEEAPAPASAAGKKGKGGGGQIAALRALMEAQQKAREEAERAA
EEERRRIEEEERRAAEEERRKEEARQAKKEKEKAKKEQLKREGKLLTPKQKAERAAAEAR
RQALLAAGNVTIAGLQEKPDQGPKKVSYGKRERAGGKKAQQTESPAESKPASPEPPKEEA
KSAPAVAEEKKDEDEEDVKDSWDASSDEEKEDVKDSWDASSDEEDEKKEEKSAAAAKPAA
NGKAAEAKSKAAAKPADDESSAEEDSDEDSDSGSDDDSDSDDDSDDDSEEEMTAVERQEA
KRKAEAKARRLARDEQALAERSTENLRSPICVIMGHVDTGKTKLLDKIRQTNVQEGEAGG
ITQQIGATYFPMDAIQKRTRVLGDDDLKEYKLPGLLVIDTPGHESFTNLRQRGSSLCNIA
ILVVDIMHGLEPQTLESIRLLREGKTPFIVALNKIDRLYGWNAMKDGGFRQTLAQQERPV
QREFEKRLNETVVAFAEQGLNAVPYYDNKNFAKYVSLVPTSAHTGEGVPDLLMLLVKLTQ
ERMANNLMYISTLQCTVLEVKVIEGLGTTIDVVLVNGYLHEGDKIVLCGLNGAIVTQVRA
LLTPQPMKELRIKGQYVHHKQIKAAMGIKIVAPDLEKAIAGSRLLVCGEDDDEDELREEV
MSDLTNLLNSVDTSGRGVFVQASTLGSLEALLEFLKSDAVRIPVAGINIGPVHKKDVMRC
ATMLERAPELAVILCFDVAVDKDAERQAEELGIKIFKADIIYHLFDQFMVYKRGVEEKKE
AEAAGKAVFPCRLKILACFAQRDPIILGCDILDGTLRIGTPLCVVKTDPKTKKKEVISLG
KVTSLEINHKSKDIVKRHEVGAGVAVKIEHAAYESAKQYGRHFDDKDEVVSMVSRESIDV
LKDVFRKQVSMDEWRLIKALKGELGIP