Protein Info for mRNA_6095 in Rhodosporidium toruloides IFO0880

Name: 14463
Annotation: KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1722 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 24 to 42 (19 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 118 to 137 (20 residues), see Phobius details amino acids 149 to 170 (22 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details amino acids 231 to 252 (22 residues), see Phobius details amino acids 312 to 338 (27 residues), see Phobius details amino acids 360 to 383 (24 residues), see Phobius details amino acids 483 to 510 (28 residues), see Phobius details amino acids 574 to 599 (26 residues), see Phobius details amino acids 1106 to 1130 (25 residues), see Phobius details amino acids 1157 to 1180 (24 residues), see Phobius details amino acids 1237 to 1268 (32 residues), see Phobius details amino acids 1291 to 1310 (20 residues), see Phobius details amino acids 1344 to 1362 (19 residues), see Phobius details amino acids 1368 to 1389 (22 residues), see Phobius details PF00664: ABC_membrane" amino acids 450 to 621 (172 residues), 71.1 bits, see alignment E=1.3e-23 amino acids 1121 to 1363 (243 residues), 103.3 bits, see alignment E=2e-33 PF00005: ABC_tran" amino acids 810 to 904 (95 residues), 33.7 bits, see alignment 4.9e-12 amino acids 1449 to 1608 (160 residues), 96.6 bits, see alignment E=1.9e-31

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1722 amino acids)

>mRNA_6095 KOG0054 Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily (Rhodosporidium toruloides IFO0880)
MLVFALSALPRSLSVHPWIPHLALTVPACVASTAVALSLPAIRTQPIQLHDDDADDAAEK
DTEVDPDHFYPHLRRTKKAAACVVLTALLALELFRVGWEPLAFGWNGWRDWVERAARVVF
WTVTFALSLLSFPHPIPSSRASLKTHWRLTVLLFTLTSSFLALTLLRWLLPRSTGLSLFP
PRESYGSASYAAQMAILLASTALQLAAFLLLGTTPHSAPLIHPSRTPAKPIITLPSTSPL
SLLLFSWISPVLHTSYASTEPMDEGTLPAIPAADRAPNAWRKIRESKGLMSTAPRGWNPL
LWRIVVVNRRLFFWQISLSVMNAVLYYVPAFFLQRLVLFLERRSNPQDPSHDTDGSLRWG
YVYCVGLLVGAVVESLVSGQLWFVSNSMLSTGIRVQLNTLIFDKTLRRKDISAPSTSSSP
SPTTSNDSNDADEGEDEEEEEGKEGGGFKTRSSLTNLFAIDSERVADFATWAFSCWDAPI
EIIIGTIFLYSLIGYAALIGIAVAVLFLPLNNWASSQFMTTQDKLMATRDRRVSLMNEVL
GSIRMIKFYAFERPFEKRILDARRDELKTLRWNYFLEVSFQGIWSISPILCILVSFWAYT
SPLLMNRQLTPSTAFTALSVWNELRFALNVVPDVLQSALQSLVSLRRIEKFLRMPEIEHL
QGMDVPVSAEGAGAAVTGLETDGSDERVAFDHATVTWPQHADEKDDDEEEDEGAQKPFEL
QDLTLEFPKGEMSLVCGRLGSGKTLLLLGASERSLSLVVLIVRAKTDHERFDRTALLGEV
DVLSGSVHCPRSPPSAIALPSLDWDAYLSDANWNAPSHTAFVPQQAWLMNDSVRNNILFG
LPFRKERYEKTLAACSLTSDLAILEDGDSTEIGEKGINLSGGQKARVSLARAVYSRAGIL
LLDDVLSAVDAHTAAHIYEQCLKGPLLKGRTVILVSHHVQLTAPGAGFVVSLENGRVAFS
GSSSEFFESDGYKAIAGDDKDVADDEPKADGVLSTSPKKPSGLSTSPRKPATFLPPNAGK
PKNKTFAQIVAEGNDSTPASSTDVTSASESGEEDESDSEPQDPTIDGDDKKKDKSSPTAK
GEHKPRKLVEEETRAVGKVSADVWKLYLGSMGGLFFWMWFVVAFAGAKLADVAQTWWLGK
WSGDAGPESAHSTNYYLILYAILSVLAAFVDTAQWFVLYAGTLRSSAVLHERLLHAVLRA
PLRWFDSQALGRIQNRFSKDLEGIDSSLPDNFGRSLMYGLGVVTTLSVVASSAPTFLLGF
ALISVLYYRDARLFQTSAREFRRLDSVSKSPLFSIYGEAIAGVAVIRAFGSSARFMAMML
DRATTNVTFYWYLWGTNRWLSMRFSLLSATVVALTGYVLISAGDKVDAALAGFTLTFALN
ISNDILFLVRRYTQLELSMVGVERTKEFSEIKQEAAEIVEPRPPAHWPTGNIEVKNLHIR
YAPELPDVLHGLTFSVKAGEKIGIVGSTGCGKSTLAASFFRFVEAHSGAIVVDGIDISKI
GLLDLRSRLTIVPQDPVILSGTLRSTLDMFEQYEDAEIFDALRRVHLIREEERPDEQEAG
TNRSVFWNLDADVAEGGSNYSTGQRQLLCMARALLKRNKILLLDEATASTDHETDELITQ
TIRQEFADATLLVIAHRLRTIIDFDKILLLDKGKLIEFESPAKLLEDPTSRFYALCRATG
RKEFAILKKMSKGKARVTHRPRKLVRRSTAKVPKAQGSNGQA