Protein Info for mRNA_6239 in Rhodosporidium toruloides IFO0880

Name: 14607
Annotation: K01372 BLMH, pepC bleomycin hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 PF03051: Peptidase_C1_2" amino acids 51 to 464 (414 residues), 452.4 bits, see alignment E=1.6e-139

Best Hits

KEGG orthology group: K01372, bleomycin hydrolase [EC: 3.4.22.40] (inferred from 45% identity to lbc:LACBIDRAFT_183606)

Predicted SEED Role

"Aminopeptidase C (EC 3.4.22.40)" in subsystem Protein degradation (EC 3.4.22.40)

Isozymes

Compare fitness of predicted isozymes for: 3.4.22.40

Use Curated BLAST to search for 3.4.22.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (539 amino acids)

>mRNA_6239 K01372 BLMH, pepC bleomycin hydrolase (Rhodosporidium toruloides IFO0880)
MGNAASTPAPQSTLSEKHNSTTRVSSPSSAADLLSQLSLRGSAASRASAKVTSENLAAWE
GDFASSPKHRLASTVLSKAALTDSLVRRDAQRNTQQIFNVKVNEGGLPITNQKSSGRCWL
FSATNLLRIALARKLDLDDFQFSQSYLFFWDSLSKANYFLEQMLDLADSPLDDRVVQHLM
NMPENDGGQWSMLDSLITTFGLVPQSVYPESFNSSNTGKLDALLTSKLREYALELRDLHS
AAMRTLSDLADGKSYAEKKVLAAQSARKKKEEQMSEVYRILAIALGQPPKPDDSFVWEYY
SKKDKKYHRVETTPKKLYGSVGVDTSKVLSLVNDPRHEYETLLSVDRLGNVWGGAPVTYV
NVDLDVLKKTAIRLLRDDTPVWFGCDVGKFSSSSLGIMSTKLWDLDEGFGTSLKMSKAQR
LETGDSAMTHAMLITAVHIDEKSGKPTRWRIENSWGPDVGEKGCVRRPRSHVFPLWADER
RGETATSSWTTSGSPSTSTKSAPTASTSTRSWSTYSTRARRPSCLPGCVLAFPAALLVC