Protein Info for mRNA_6333 in Rhodosporidium toruloides IFO0880

Name: 14701
Annotation: K08852 ERN1 serine/threonine-protein kinase/endoribonuclease IRE1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1357 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 600 to 620 (21 residues), see Phobius details PF00069: Pkinase" amino acids 924 to 1100 (177 residues), 107.4 bits, see alignment E=1.3e-34 PF07714: Pkinase_Tyr" amino acids 924 to 1099 (176 residues), 57.4 bits, see alignment E=2.2e-19 PF06479: Ribonuc_2-5A" amino acids 1224 to 1349 (126 residues), 154.8 bits, see alignment E=1.9e-49

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1357 amino acids)

>mRNA_6333 K08852 ERN1 serine/threonine-protein kinase/endoribonuclease IRE1 (Rhodosporidium toruloides IFO0880)
MPPTARRTPLSHLTSPFLALGSLAPSSTNAAPEPAALAPRHDQPAGGRDPAALPAHLRDR
SKAQHQDRLPDAIRGVRFNAPLRPPPLPARPANEASEGDDAGFALSQLVLAVTVDGQVHA
LKRETGQWVWTLHDDGGIALGGVGRGSAEERRRRSGAGDAVGGPLVKSLSRKRRAPPTAS
SSRSTILSNETSVIAVDAVDEDDDETYIIEPSGSGDVYVYSRSSGGLEKLPLSMQELVAL
SPFRFPGDSSRMFSASKNTKFVGVDLKTGRLVGVFGSNAGWCEWDEADELTAGARAAEQD
CEEDIAKRPEDLLYMARTEYHLSIYDTSSSQPLQTLSYTTYTSSALPHVSTPASSGTYPS
QSTWTRTPDSLYLQPMHDGSLVCFRAGQAGVQWSIDFEAPVVSVFDVVVPFPSTSSPSIE
GADPHPVMFEQPHPLLVPDLPLDFSVLQQEPAATFIGRVVSPATGEEQLFAMSRDRFPLV
PFAQVAEAAKAGLGEQEAQEEGKEEVKEKPESCRGVDCIIGRHRLLHPPPASPLDATIDA
PTEPLLIDAAPSSSLPSPSAPHDSLSTPNRRTPHLPGSSTLLARLSSSSVMRELSGHGEV
LAGGRLTVGVMVLVLVGWWWSRWRKVEEGKNEEEGKRRSGRRTRGRGKKQQQQQVEANGG
EASGTATPRGGANQSNGLEFANVRGETVVAVPSVAPSPSVEGLRKRSPSTPPTPTNLSFA
PLSSSSASGSSTPARARASSLSLAPAFPLSSTLKELPPLPPSALLDSDDTEELLNGSPSL
SSSVDLTDQPDDGADSDSAPSSVAPGAAPGTPPRKRQRRRRGAKKKKPKDGQGMDDVAVG
AVDEKDLLEGITLSERETRDEEADNSEEAAGVSAQVDVDGKGVDGDVAGASAPVSAAIGA
GEVNAVAKSARLDPQVVGGLAVSEEILGYGSHGTVVLRGEFQGRAVAVKRLLKDFVTIAA
HEVNLLQESDDHPHVIRYFCKEQRETFLYIALELCPASLFDLVDQPSAFPDLVRQLDPKK
ALKQITSGLRHLHSLKIVHRDIKPQNILVSTAKRGQPGLRMLISDFGLCKKLDVDESSFQ
QTVNHAAGSFGYRAPEVLRGLVDPNEGATGTSSASAGSGGSSTTLAGLTTTDPSMRLTRS
IDIFSLGCIFYYVLTRGDHPFGGRYEREMNILNGKASLDRLDGLGEEAVEVQDLILRMVA
TDPRERPTADAVLLHPFFWNAQKRLLFICDASDRFEIMERDPPTATLVTLESRAREIVGD
DWQKALDRTFLENLGKYRKYDGASVRDLLRVLRNKKHHYQDLPEGVQRALGDLPGGFLSY
FTTRFPHLLLHVYDTVARHLADEPMFASTFRIPEDEA